Liang PH - Search Results

1

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.

Shao YM, Yang WB, Peng HP, Hsu MF, Tsai KC, Kuo TH, Wang AH, Liang PH, Lin CH, Yang AS, Wong CH. Shao YM, et al. Among authors: liang ph. Chembiochem. 2007 Sep 24;8(14):1654-7. doi: 10.1002/cbic.200700254. Chembiochem. 2007. PMID: 17722121 Free PMC article.

2

Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.

Ko TP, Chen YK, Robinson H, Tsai PC, Gao YG, Chen AP, Wang AH, Liang PH. Ko TP, et al. Among authors: liang ph. J Biol Chem. 2001 Dec 14;276(50):47474-82. doi: 10.1074/jbc.M106747200. Epub 2001 Oct 1. J Biol Chem. 2001. PMID: 11581264 Free article.

3

Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants.

Chen YH, Chen AP, Chen CT, Wang AH, Liang PH. Chen YH, et al. Among authors: liang ph. J Biol Chem. 2002 Mar 1;277(9):7369-76. doi: 10.1074/jbc.M110014200. Epub 2001 Dec 14. J Biol Chem. 2002. PMID: 11744728 Free article.

4

Insight into the activation mechanism of Escherichia coli octaprenyl pyrophosphate synthase derived from pre-steady-state kinetic analysis.

Pan JJ, Kuo TH, Chen YK, Yang LW, Liang PH. Pan JJ, et al. Among authors: liang ph. Biochim Biophys Acta. 2002 Jan 31;1594(1):64-73. doi: 10.1016/s0167-4838(01)00283-7. Biochim Biophys Acta. 2002. PMID: 11825609

5

Structure, mechanism and function of prenyltransferases.

Liang PH, Ko TP, Wang AH. Liang PH, et al. Eur J Biochem. 2002 Jul;269(14):3339-54. doi: 10.1046/j.1432-1033.2002.03014.x. Eur J Biochem. 2002. PMID: 12135472 Free article. Review.

6

Reaction kinetic pathway of the recombinant octaprenyl pyrophosphate synthase from Thermotoga maritima: how is it different from that of the mesophilic enzyme.

Kuo TH, Liang PH. Kuo TH, et al. Among authors: liang ph. Biochim Biophys Acta. 2002 Sep 23;1599(1-2):125-33. doi: 10.1016/s1570-9639(02)00410-7. Biochim Biophys Acta. 2002. PMID: 12479413

7

Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton.

Chang SY, Ko TP, Liang PH, Wang AH. Chang SY, et al. Among authors: liang ph. J Biol Chem. 2003 Aug 1;278(31):29298-307. doi: 10.1074/jbc.M302687200. Epub 2003 May 19. J Biol Chem. 2003. PMID: 12756244 Free article.

8

Crystal structure of octaprenyl pyrophosphate synthase from hyperthermophilic Thermotoga maritima and mechanism of product chain length determination.

Guo RT, Kuo CJ, Chou CC, Ko TP, Shr HL, Liang PH, Wang AH. Guo RT, et al. Among authors: liang ph. J Biol Chem. 2004 Feb 6;279(6):4903-12. doi: 10.1074/jbc.M310161200. Epub 2003 Nov 15. J Biol Chem. 2004. PMID: 14617622 Free article.

9

Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli.

Guo RT, Ko TP, Chou CC, Shr HL, Chu HM, Tsai YH, Liang PH, Wang AH. Guo RT, et al. Among authors: liang ph. Acta Crystallogr D Biol Crystallogr. 2003 Dec;59(Pt 12):2265-8. doi: 10.1107/s0907444903018985. Epub 2003 Nov 27. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 14646090

10

Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase.

Chang SY, Chen YK, Wang AH, Liang PH. Chang SY, et al. Among authors: liang ph. Biochemistry. 2003 Dec 16;42(49):14452-9. doi: 10.1021/bi035283x. Biochemistry. 2003. PMID: 14661956

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