Wang AH - Search Results

1

Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.

Shao YM, Yang WB, Peng HP, Hsu MF, Tsai KC, Kuo TH, Wang AH, Liang PH, Lin CH, Yang AS, Wong CH. Shao YM, et al. Among authors: wang ah. Chembiochem. 2007 Sep 24;8(14):1654-7. doi: 10.1002/cbic.200700254. Chembiochem. 2007. PMID: 17722121 Free PMC article.

2

Mechanism of the maturation process of SARS-CoV 3CL protease.

Hsu MF, Kuo CJ, Chang KT, Chang HC, Chou CC, Ko TP, Shr HL, Chang GG, Wang AH, Liang PH. Hsu MF, et al. Among authors: wang ah. J Biol Chem. 2005 Sep 2;280(35):31257-66. doi: 10.1074/jbc.M502577200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788388 Free PMC article.

3

Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.

Lee CC, Kuo CJ, Hsu MF, Liang PH, Fang JM, Shie JJ, Wang AH. Lee CC, et al. Among authors: wang ah. FEBS Lett. 2007 Nov 27;581(28):5454-8. doi: 10.1016/j.febslet.2007.10.048. Epub 2007 Nov 5. FEBS Lett. 2007. PMID: 17981158 Free PMC article.

4

Structure, mechanism and function of prenyltransferases.

Liang PH, Ko TP, Wang AH. Liang PH, et al. Among authors: wang ah. Eur J Biochem. 2002 Jul;269(14):3339-54. doi: 10.1046/j.1432-1033.2002.03014.x. Eur J Biochem. 2002. PMID: 12135472 Free article. Review.

5

Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton.

Chang SY, Ko TP, Liang PH, Wang AH. Chang SY, et al. Among authors: wang ah. J Biol Chem. 2003 Aug 1;278(31):29298-307. doi: 10.1074/jbc.M302687200. Epub 2003 May 19. J Biol Chem. 2003. PMID: 12756244 Free article.

6

Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor.

Yang S, Chen SJ, Hsu MF, Wu JD, Tseng CT, Liu YF, Chen HC, Kuo CW, Wu CS, Chang LW, Chen WC, Liao SY, Chang TY, Hung HH, Shr HL, Liu CY, Huang YA, Chang LY, Hsu JC, Peters CJ, Wang AH, Hsu MC. Yang S, et al. Among authors: wang ah. J Med Chem. 2006 Aug 10;49(16):4971-80. doi: 10.1021/jm0603926. J Med Chem. 2006. PMID: 16884309

7

Probing the conformational change of Escherichia coli undecaprenyl pyrophosphate synthase during catalysis using an inhibitor and tryptophan mutants.

Chen YH, Chen AP, Chen CT, Wang AH, Liang PH. Chen YH, et al. Among authors: wang ah. J Biol Chem. 2002 Mar 1;277(9):7369-76. doi: 10.1074/jbc.M110014200. Epub 2001 Dec 14. J Biol Chem. 2002. PMID: 11744728 Free article.

8

Identification of the active conformation and the importance of length of the flexible loop 72-83 in regulating the conformational change of undecaprenyl pyrophosphate synthase.

Chang SY, Chen YK, Wang AH, Liang PH. Chang SY, et al. Among authors: wang ah. Biochemistry. 2003 Dec 16;42(49):14452-9. doi: 10.1021/bi035283x. Biochemistry. 2003. PMID: 14661956

9

Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies.

Chang SY, Ko TP, Chen AP, Wang AH, Liang PH. Chang SY, et al. Among authors: wang ah. Protein Sci. 2004 Apr;13(4):971-8. doi: 10.1110/ps.03519904. Protein Sci. 2004. PMID: 15044730 Free PMC article.

10

Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis.

Guo RT, Ko TP, Chen AP, Kuo CJ, Wang AH, Liang PH. Guo RT, et al. Among authors: wang ah. J Biol Chem. 2005 May 27;280(21):20762-74. doi: 10.1074/jbc.M502121200. Epub 2005 Mar 23. J Biol Chem. 2005. PMID: 15788389 Free article.

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