Hibbs RE - Search Results

1

Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes.

Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J. Taylor P, et al. Among authors: hibbs re. Biochem Pharmacol. 2007 Oct 15;74(8):1164-71. doi: 10.1016/j.bcp.2007.07.038. Epub 2007 Aug 3. Biochem Pharmacol. 2007. PMID: 17826748 Free PMC article. Review.

2

Contemporary paradigms for cholinergic ligand design guided by biological structure.

Taylor P, Hansen SB, Talley TT, Hibbs RE, Radić Z. Taylor P, et al. Among authors: hibbs re. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1875-7. doi: 10.1016/j.bmcl.2003.10.072. Bioorg Med Chem Lett. 2004. PMID: 15050619 Free PMC article. Review.

3

Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein.

Hibbs RE, Talley TT, Taylor P. Hibbs RE, et al. J Biol Chem. 2004 Jul 2;279(27):28483-91. doi: 10.1074/jbc.M403713200. Epub 2004 Apr 26. J Biol Chem. 2004. PMID: 15117947 Free article.

4

Structural dynamics of the alpha-neurotoxin-acetylcholine-binding protein complex: hydrodynamic and fluorescence anisotropy decay analyses.

Hibbs RE, Johnson DA, Shi J, Hansen SB, Taylor P. Hibbs RE, et al. Biochemistry. 2005 Dec 20;44(50):16602-11. doi: 10.1021/bi051735p. Biochemistry. 2005. PMID: 16342951

5

Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein.

Hibbs RE, Radic Z, Taylor P, Johnson DA. Hibbs RE, et al. J Biol Chem. 2006 Dec 22;281(51):39708-18. doi: 10.1074/jbc.M604752200. Epub 2006 Oct 26. J Biol Chem. 2006. PMID: 17068341 Free article.

6

Structural dynamics of the acetylcholine binding protein: hydrodynamic and fluorescence anisotropy decay analyses.

Hibbs RE, Johnson DA, Shi J, Taylor P. Hibbs RE, et al. J Mol Neurosci. 2006;30(1-2):73-4. doi: 10.1385/JMN:30:1:73. J Mol Neurosci. 2006. PMID: 17192634

7

Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore.

Talley TT, Harel M, Hibbs RE, Radic Z, Tomizawa M, Casida JE, Taylor P. Talley TT, et al. Among authors: hibbs re. Proc Natl Acad Sci U S A. 2008 May 27;105(21):7606-11. doi: 10.1073/pnas.0802197105. Epub 2008 May 13. Proc Natl Acad Sci U S A. 2008. PMID: 18477694 Free PMC article.

8

Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.

Hibbs RE, Sulzenbacher G, Shi J, Talley TT, Conrod S, Kem WR, Taylor P, Marchot P, Bourne Y. Hibbs RE, et al. EMBO J. 2009 Oct 7;28(19):3040-51. doi: 10.1038/emboj.2009.227. Epub 2009 Aug 20. EMBO J. 2009. PMID: 19696737 Free PMC article.

9

Heteromeric Neuronal Nicotinic Acetylcholine Receptors with Mutant β Subunits Acquire Sensitivity to α7-Selective Positive Allosteric Modulators.

Stokes C, Garai S, Kulkarni AR, Cantwell LN, Noviello CM, Hibbs RE, Horenstein NA, Abboud KA, Thakur GA, Papke RL. Stokes C, et al. Among authors: hibbs re. J Pharmacol Exp Ther. 2019 Aug;370(2):252-268. doi: 10.1124/jpet.119.259499. Epub 2019 Jun 7. J Pharmacol Exp Ther. 2019. PMID: 31175218 Free PMC article.

10

Structural bases for stoichiometry-selective calcium potentiation of a neuronal nicotinic receptor.

Mazzaferro S, Kang G, Natarajan K, Hibbs RE, Sine SM. Mazzaferro S, et al. Among authors: hibbs re. Br J Pharmacol. 2024 Jul;181(13):1973-1992. doi: 10.1111/bph.16321. Epub 2024 Mar 7. Br J Pharmacol. 2024. PMID: 38454578

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