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535 results

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Page 1
Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor.
Teng M, Johnson MD, Thomas C, Kiel D, Lakis JN, Kercher T, Aytes S, Kostrowicki J, Bhumralkar D, Truesdale L, May J, Sidelman U, Kodra JT, Jørgensen AS, Olesen PH, de Jong JC, Madsen P, Behrens C, Pettersson I, Knudsen LB, Holst JJ, Lau J. Teng M, et al. Among authors: kiel d. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5472-8. doi: 10.1016/j.bmcl.2007.06.086. Epub 2007 Jul 4. Bioorg Med Chem Lett. 2007. PMID: 17827014
Human glucagon receptor antagonists based on alkylidene hydrazides.
Ling A, Plewe M, Gonzalez J, Madsen P, Sams CK, Lau J, Gregor V, Murphy D, Teston K, Kuki A, Shi S, Truesdale L, Kiel D, May J, Lakis J, Anderes K, Iatsimirskaia E, Sidelmann UG, Knudsen LB, Brand CL, Polinsky A. Ling A, et al. Among authors: kiel d. Bioorg Med Chem Lett. 2002 Feb 25;12(4):663-6. doi: 10.1016/s0960-894x(01)00819-8. Bioorg Med Chem Lett. 2002. PMID: 11844695
Optimization of alkylidene hydrazide based human glucagon receptor antagonists. Discovery of the highly potent and orally available 3-cyano-4-hydroxybenzoic acid [1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide.
Madsen P, Ling A, Plewe M, Sams CK, Knudsen LB, Sidelmann UG, Ynddal L, Brand CL, Andersen B, Murphy D, Teng M, Truesdale L, Kiel D, May J, Kuki A, Shi S, Johnson MD, Teston KA, Feng J, Lakis J, Anderes K, Gregor V, Lau J. Madsen P, et al. Among authors: kiel d. J Med Chem. 2002 Dec 19;45(26):5755-75. doi: 10.1021/jm0208572. J Med Chem. 2002. PMID: 12477359
Identification of alkylidene hydrazides as glucagon receptor antagonists.
Ling A, Hong Y, Gonzalez J, Gregor V, Polinsky A, Kuki A, Shi S, Teston K, Murphy D, Porter J, Kiel D, Lakis J, Anderes K, May J, Knudsen LB, Lau J. Ling A, et al. Among authors: kiel d. J Med Chem. 2001 Sep 13;44(19):3141-9. doi: 10.1021/jm000547o. J Med Chem. 2001. PMID: 11543683
Small-molecule agonists for the glucagon-like peptide 1 receptor.
Knudsen LB, Kiel D, Teng M, Behrens C, Bhumralkar D, Kodra JT, Holst JJ, Jeppesen CB, Johnson MD, de Jong JC, Jorgensen AS, Kercher T, Kostrowicki J, Madsen P, Olesen PH, Petersen JS, Poulsen F, Sidelmann UG, Sturis J, Truesdale L, May J, Lau J. Knudsen LB, et al. Among authors: kiel d. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):937-42. doi: 10.1073/pnas.0605701104. Epub 2007 Jan 9. Proc Natl Acad Sci U S A. 2007. PMID: 17213325 Free PMC article.
Cloning of GRK2 cDNA from S49 murine lymphoma cells.
Hughes RJ, Anderson KL, Kiel D, Insel PA. Hughes RJ, et al. Among authors: kiel d. Am J Physiol. 1996 Mar;270(3 Pt 1):C885-91. doi: 10.1152/ajpcell.1996.270.3.C885. Am J Physiol. 1996. PMID: 8638670
Withdrawal notice to: Impact of Provision of Abdominal Aortic Calcification Results on Cardiovascular Risk Reducing Behaviours: A 12-Week RCT [Heart, Lung and Circulation, Volume 33, Supplement 4, August 2024, Page S357].
Radavelli Bagatini S, Bondonno C, Dalla Via J, Sim M, Gebre A, Blekkenhorst L, Connolly E, Bondonno N, Schousboe J, Woodman R, Zhu K, Mullin S, Szulc P, Jackson B, Dimmock J, Schlaich M, Cox K, Kiel D, Lim W, Stanley M, Devine A, Thompson P, Williams E, Wood L, Sim M, Daly R, Hodgson J, Lewis J. Radavelli Bagatini S, et al. Among authors: kiel d. Heart Lung Circ. 2024 Nov;33(11):R1. doi: 10.1016/j.hlc.2024.10.005. Heart Lung Circ. 2024. PMID: 39521576 No abstract available.
535 results