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27 results

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Page 1
Irinotecan (CPT-11) metabolism and disposition in cancer patients.
Sparreboom A, de Jonge MJ, de Bruijn P, Brouwer E, Nooter K, Loos WJ, van Alphen RJ, Mathijssen RH, Stoter G, Verweij J. Sparreboom A, et al. Among authors: van alphen rj. Clin Cancer Res. 1998 Nov;4(11):2747-54. Clin Cancer Res. 1998. PMID: 9829738 Clinical Trial.
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11).
Mathijssen RH, van Alphen RJ, Verweij J, Loos WJ, Nooter K, Stoter G, Sparreboom A. Mathijssen RH, et al. Among authors: van alphen rj. Clin Cancer Res. 2001 Aug;7(8):2182-94. Clin Cancer Res. 2001. PMID: 11489791 Review.
The spliceosome as target for anticancer treatment.
van Alphen RJ, Wiemer EA, Burger H, Eskens FA. van Alphen RJ, et al. Br J Cancer. 2009 Jan 27;100(2):228-32. doi: 10.1038/sj.bjc.6604801. Epub 2008 Nov 25. Br J Cancer. 2009. PMID: 19034274 Free PMC article. Review.
Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment.
de Graan AJ, Teunissen SF, de Vos FY, Loos WJ, van Schaik RH, de Jongh FE, de Vos AI, van Alphen RJ, van der Holt B, Verweij J, Seynaeve C, Beijnen JH, Mathijssen RH. de Graan AJ, et al. Among authors: van alphen rj, van der holt b, van schaik rh. J Clin Oncol. 2011 Aug 20;29(24):3240-6. doi: 10.1200/JCO.2010.32.9839. Epub 2011 Jul 18. J Clin Oncol. 2011. PMID: 21768449 Clinical Trial.
The OCT2/MATE1 Interaction Between Trifluridine, Metformin and Cimetidine: A Crossover Pharmacokinetic Study.
Guchelaar NAD, Buck SAJ, van Doorn L, Hussaarts KGAM, Sandberg Y, van der Padt-Pruijsten A, van Alphen RJ, Poppe-Manenschijn L, Vleut I, de Bruijn P, van Leeuwen RWF, Mostert B, Eskens FALM, Oomen-de Hoop E, Koolen SLW, Mathijssen RHJ. Guchelaar NAD, et al. Among authors: van alphen rj. Clin Pharmacokinet. 2024 Jul;63(7):1037-1044. doi: 10.1007/s40262-024-01390-3. Epub 2024 Jun 28. Clin Pharmacokinet. 2024. PMID: 38951433 Free PMC article. Clinical Trial.
Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients.
Binkhorst L, Kloth JSL, de Wit AS, de Bruijn P, Lam MH, Chaves I, Burger H, van Alphen RJ, Hamberg P, van Schaik RHN, Jager A, Koch BCP, Wiemer EAC, van Gelder T, van der Horst GTJ, Mathijssen RHJ. Binkhorst L, et al. Among authors: van gelder t, van alphen rj, van schaik rhn, van der horst gtj. Breast Cancer Res Treat. 2015 Jul;152(1):119-128. doi: 10.1007/s10549-015-3452-x. Epub 2015 Jun 7. Breast Cancer Res Treat. 2015. PMID: 26050156 Free PMC article.
Augmentation of Endoxifen Exposure in Tamoxifen-Treated Women Following SSRI Switch.
Binkhorst L, Bannink M, de Bruijn P, Ruit J, Droogendijk H, van Alphen RJ, den Boer TD, Lam MH, Jager A, van Gelder T, Mathijssen RH. Binkhorst L, et al. Among authors: van gelder t, van alphen rj. Clin Pharmacokinet. 2016 Feb;55(2):249-55. doi: 10.1007/s40262-015-0315-x. Clin Pharmacokinet. 2016. PMID: 26446141 Free PMC article. Clinical Trial.
27 results