Hou C - Search Results

1

Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.

Xia M, Hou C, Pollack S, Brackley J, DeMong D, Pan M, Singer M, Matheis M, Olini G, Cavender D, Wachter M. Xia M, et al. Among authors: hou c. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5964-8. doi: 10.1016/j.bmcl.2007.07.065. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17869105

2

Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

Lagu B, Gerchak C, Pan M, Hou C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Lagu B, et al. Among authors: hou c. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4382-6. doi: 10.1016/j.bmcl.2007.01.115. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17587570

3

Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

Xia M, Hou C, DeMong DE, Pollack SR, Pan M, Brackley JA, Jain N, Gerchak C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Xia M, et al. Among authors: hou c. J Med Chem. 2007 Nov 15;50(23):5561-3. doi: 10.1021/jm070902b. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929797

4

Substituted dipiperidine alcohols as potent CCR2 antagonists.

Xia M, Hou C, Demong D, Pollack S, Pan M, Brackley J, Singer M, Matheis M, Cavender D, Wachter M. Xia M, et al. Among authors: hou c. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3562-4. doi: 10.1016/j.bmcl.2008.05.010. Epub 2008 May 4. Bioorg Med Chem Lett. 2008. PMID: 18487045

5

Synthesis and structure-activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists.

Xia M, Hou C, DeMong D, Pollack S, Pan M, Singer M, Matheis M, Murray W, Cavender D, Wachter M. Xia M, et al. Among authors: hou c. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6468-70. doi: 10.1016/j.bmcl.2008.10.061. Epub 2008 Oct 17. Bioorg Med Chem Lett. 2008. PMID: 18990568

6

Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.

Zhang X, Hufnagel H, Markotan T, Lanter J, Cai C, Hou C, Singer M, Opas E, McKenney S, Crysler C, Johnson D, Sui Z. Zhang X, et al. Among authors: hou c. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5577-82. doi: 10.1016/j.bmcl.2011.06.080. Epub 2011 Jun 29. Bioorg Med Chem Lett. 2011. PMID: 21783361

7

The discovery of novel cyclohexylamide CCR2 antagonists.

Lanter JC, Markotan TP, Zhang X, Subasinghe N, Kang FA, Hou C, Singer M, Opas E, McKenney S, Crysler C, Johnson D, Molloy CJ, Sui Z. Lanter JC, et al. Among authors: hou c. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7496-501. doi: 10.1016/j.bmcl.2011.09.113. Epub 2011 Oct 8. Bioorg Med Chem Lett. 2011. PMID: 22061641

8

Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists.

Zhang X, Hufnagel H, Hou C, Opas E, McKenney S, Crysler C, O'Neill J, Johnson D, Sui Z. Zhang X, et al. Among authors: hou c. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6042-8. doi: 10.1016/j.bmcl.2011.08.074. Epub 2011 Aug 22. Bioorg Med Chem Lett. 2011. PMID: 21917454

9

In vivo activity of a phospholipase C inhibitor, 1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in acute and chronic inflammatory reactions.

Hou C, Kirchner T, Singer M, Matheis M, Argentieri D, Cavender D. Hou C, et al. J Pharmacol Exp Ther. 2004 May;309(2):697-704. doi: 10.1124/jpet.103.060574. Epub 2004 Jan 16. J Pharmacol Exp Ther. 2004. PMID: 14730005

10

Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists.

Cai C, Kang FA, Hou C, O'Neill JC, Opas E, McKenney S, Johnson D, Sui Z. Cai C, et al. Among authors: hou c. Bioorg Med Chem Lett. 2013 Jan 1;23(1):351-4. doi: 10.1016/j.bmcl.2012.10.069. Epub 2012 Oct 24. Bioorg Med Chem Lett. 2013. PMID: 23182090

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

4,684 results

Search Page

Filters