Darby JM - Search Results

1

The La autoantigen is a malignancy-associated cell death target that is induced by DNA-damaging drugs.

Al-Ejeh F, Darby JM, Brown MP. Al-Ejeh F, et al. Among authors: darby jm. Clin Cancer Res. 2007 Sep 15;13(18 Pt 2):5509s-5518s. doi: 10.1158/1078-0432.CCR-07-0922. Clin Cancer Res. 2007. PMID: 17875783

2

In vivo targeting of dead tumor cells in a murine tumor model using a monoclonal antibody specific for the La autoantigen.

Al-Ejeh F, Darby JM, Pensa K, Diener KR, Hayball JD, Brown MP. Al-Ejeh F, et al. Among authors: darby jm. Clin Cancer Res. 2007 Sep 15;13(18 Pt 2):5519s-5527s. doi: 10.1158/1078-0432.CCR-07-0964. Clin Cancer Res. 2007. PMID: 17875784

3

Chemotherapy synergizes with radioimmunotherapy targeting La autoantigen in tumors.

Al-Ejeh F, Darby JM, Brown MP. Al-Ejeh F, et al. Among authors: darby jm. PLoS One. 2009;4(2):e4630. doi: 10.1371/journal.pone.0004630. Epub 2009 Feb 27. PLoS One. 2009. PMID: 19247485 Free PMC article.

4

APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy.

Al-Ejeh F, Darby JM, Tsopelas C, Smyth D, Manavis J, Brown MP. Al-Ejeh F, et al. Among authors: darby jm. PLoS One. 2009;4(2):e4558. doi: 10.1371/journal.pone.0004558. Epub 2009 Feb 27. PLoS One. 2009. PMID: 19247492 Free PMC article.

5

A simplified suite of methods to evaluate chelator conjugation of antibodies: effects on hydrodynamic radius and biodistribution.

Al-Ejeh F, Darby JM, Thierry B, Brown MP. Al-Ejeh F, et al. Among authors: darby jm. Nucl Med Biol. 2009 May;36(4):395-402. doi: 10.1016/j.nucmedbio.2009.01.001. Epub 2009 Mar 26. Nucl Med Biol. 2009. PMID: 19423007

6

The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®.

Staudacher AH, Al-Ejeh F, Fraser CK, Darby JM, Roder DM, Ruszkiewicz A, Manavis J, Brown MP. Staudacher AH, et al. Among authors: darby jm. EJNMMI Res. 2014 Jan 4;4(1):2. doi: 10.1186/2191-219X-4-2. EJNMMI Res. 2014. PMID: 24387284 Free PMC article.

7

Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance.

Al-Ejeh F, Staudacher AH, Smyth DR, Darby JM, Denoyer D, Tsopelas C, Hicks RJ, Brown MP. Al-Ejeh F, et al. Among authors: darby jm. J Nucl Med. 2014 May;55(5):772-9. doi: 10.2967/jnumed.113.130559. Epub 2014 Mar 27. J Nucl Med. 2014. PMID: 24676755 Free article.

8

Pro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis.

Ong ZY, Gibson RJ, Bowen JM, Stringer AM, Darby JM, Logan RM, Yeoh AS, Keefe DM. Ong ZY, et al. Among authors: darby jm. Radiat Oncol. 2010 Mar 16;5:22. doi: 10.1186/1748-717X-5-22. Radiat Oncol. 2010. PMID: 20233440 Free PMC article.

9

NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers.

Ong CEB, Patchett AL, Darby JM, Chen J, Liu GS, Lyons AB, Woods GM, Flies AS. Ong CEB, et al. Among authors: darby jm. J Cancer Res Clin Oncol. 2021 Jul;147(7):1973-1991. doi: 10.1007/s00432-021-03601-x. Epub 2021 Apr 2. J Cancer Res Clin Oncol. 2021. PMID: 33797607 Free PMC article.

10

The Immunomodulatory Small Molecule Imiquimod Induces Apoptosis in Devil Facial Tumour Cell Lines.

Patchett AL, Darby JM, Tovar C, Lyons AB, Woods GM. Patchett AL, et al. Among authors: darby jm. PLoS One. 2016 Dec 9;11(12):e0168068. doi: 10.1371/journal.pone.0168068. eCollection 2016. PLoS One. 2016. PMID: 27936237 Free PMC article.

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