Hart LS - Search Results

1

Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4.

Sussman RT, Ricci MS, Hart LS, Sun SY, El-Deiry WS. Sussman RT, et al. Among authors: hart ls. Cancer Biol Ther. 2007 Sep;6(9):1490-5. doi: 10.4161/cbt.6.9.4905. Epub 2007 Aug 17. Cancer Biol Ther. 2007. PMID: 17881904 Free article.

2

Effects of low confluency, serum starvation and hypoxia on the side population of cancer cell lines.

Tavaluc RT, Hart LS, Dicker DT, El-Deiry WS. Tavaluc RT, et al. Among authors: hart ls. Cell Cycle. 2007 Oct 15;6(20):2554-62. doi: 10.4161/cc.6.20.4911. Epub 2007 Aug 21. Cell Cycle. 2007. PMID: 17912032

3

Invincible, but not invisible: imaging approaches toward in vivo detection of cancer stem cells.

Hart LS, El-Deiry WS. Hart LS, et al. J Clin Oncol. 2008 Jun 10;26(17):2901-10. doi: 10.1200/JCO.2008.16.9573. J Clin Oncol. 2008. PMID: 18539971 Review.

4

Cell death: a new Par-4 the TRAIL.

Hart LS, El-Deiry WS. Hart LS, et al. Cell. 2009 Jul 23;138(2):220-2. doi: 10.1016/j.cell.2009.07.007. Cell. 2009. PMID: 19632170 Free article.

5

Visualization and enrichment of live putative cancer stem cell populations following p53 inactivation or Bax deletion using non-toxic fluorescent dyes.

Allen JE, Hart LS, Dicker DT, Wang W, El-Deiry WS. Allen JE, et al. Among authors: hart ls. Cancer Biol Ther. 2009 Nov;8(22):2194-205. doi: 10.4161/cbt.8.22.10450. Epub 2009 Nov 27. Cancer Biol Ther. 2009. PMID: 19923899 Free PMC article.

6

The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells.

Huang C, Zhang XM, Tavaluc RT, Hart LS, Dicker DT, Wang W, El-Deiry WS. Huang C, et al. Among authors: hart ls. Cancer Biol Ther. 2009 Nov;8(22):2186-93. doi: 10.4161/cbt.8.22.10446. Epub 2009 Nov 27. Cancer Biol Ther. 2009. PMID: 19923910 Free PMC article.

7

Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.

Mayes PA, Dolloff NG, Daniel CJ, Liu JJ, Hart LS, Kuribayashi K, Allen JE, Jee DI, Dorsey JF, Liu YY, Dicker DT, Brown JM, Furth EE, Klein PS, Sears RC, El-Deiry WS. Mayes PA, et al. Among authors: hart ls. Cancer Res. 2011 Aug 1;71(15):5265-75. doi: 10.1158/0008-5472.CAN-11-1383. Epub 2011 Jun 6. Cancer Res. 2011. PMID: 21646472 Free PMC article.

8

Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.

Dolloff NG, Mayes PA, Hart LS, Dicker DT, Humphreys R, El-Deiry WS. Dolloff NG, et al. Among authors: hart ls. Sci Transl Med. 2011 Jun 8;3(86):86ra50. doi: 10.1126/scitranslmed.3001384. Sci Transl Med. 2011. PMID: 21653830 Free PMC article.

9

Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab.

Hart LS, Dolloff NG, Dicker DT, Koumenis C, Christensen JG, Grimberg A, El-Deiry WS. Hart LS, et al. Cell Cycle. 2011 Jul 15;10(14):2331-8. doi: 10.4161/cc.10.14.16418. Epub 2011 Jul 15. Cell Cycle. 2011. PMID: 21720213 Free PMC article.

10

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.

Matthew EM, Hart LS, Astrinidis A, Navaraj A, Dolloff NG, Dicker DT, Henske EP, El-Deiry WS. Matthew EM, et al. Among authors: hart ls. Cell Cycle. 2009 Dec 15;8(24):4168-75. doi: 10.4161/cc.8.24.10800. Cell Cycle. 2009. PMID: 20054236 Free PMC article.

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