Gaestel M - Search Results

1

Systemic deficiency of the MAP kinase-activated protein kinase 2 reduces atherosclerosis in hypercholesterolemic mice.

Jagavelu K, Tietge UJ, Gaestel M, Drexler H, Schieffer B, Bavendiek U. Jagavelu K, et al. Among authors: gaestel m. Circ Res. 2007 Nov 26;101(11):1104-12. doi: 10.1161/CIRCRESAHA.107.156075. Epub 2007 Sep 20. Circ Res. 2007. PMID: 17885219

2

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Müller M, Gaestel M, Resch K, Holtmann H. Winzen R, et al. Among authors: gaestel m. EMBO J. 1999 Sep 15;18(18):4969-80. doi: 10.1093/emboj/18.18.4969. EMBO J. 1999. PMID: 10487749 Free PMC article.

3

Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?

Kotlyarov A, Gaestel M. Kotlyarov A, et al. Among authors: gaestel m. Biochem Soc Trans. 2002 Nov;30(Pt 6):959-63. doi: 10.1042/bst0300959. Biochem Soc Trans. 2002. PMID: 12440954 Review.

4

Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination.

Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, Marcus K, Meyer HE, Friedrich A, Volk HD, Gaestel M. Shi Y, et al. Among authors: gaestel m. Mol Cell Biol. 2003 Nov;23(21):7732-41. doi: 10.1128/MCB.23.21.7732-7741.2003. Mol Cell Biol. 2003. PMID: 14560018 Free PMC article.

5

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element.

Hitti E, Iakovleva T, Brook M, Deppenmeier S, Gruber AD, Radzioch D, Clark AR, Blackshear PJ, Kotlyarov A, Gaestel M. Hitti E, et al. Among authors: gaestel m. Mol Cell Biol. 2006 Mar;26(6):2399-407. doi: 10.1128/MCB.26.6.2399-2407.2006. Mol Cell Biol. 2006. PMID: 16508014 Free PMC article.

6

Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress.

Vertii A, Hakim C, Kotlyarov A, Gaestel M. Vertii A, et al. Among authors: gaestel m. J Biol Chem. 2006 Sep 15;281(37):26966-75. doi: 10.1074/jbc.M602134200. Epub 2006 Jul 13. J Biol Chem. 2006. PMID: 16840785 Free article.

7

Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.

Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. Kant S, et al. Among authors: gaestel m. J Biol Chem. 2006 Nov 17;281(46):35511-9. doi: 10.1074/jbc.M606693200. Epub 2006 Sep 13. J Biol Chem. 2006. PMID: 16973613 Free article.

8

The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

Ronkina N, Kotlyarov A, Dittrich-Breiholz O, Kracht M, Hitti E, Milarski K, Askew R, Marusic S, Lin LL, Gaestel M, Telliez JB. Ronkina N, et al. Among authors: gaestel m. Mol Cell Biol. 2007 Jan;27(1):170-81. doi: 10.1128/MCB.01456-06. Epub 2006 Oct 9. Mol Cell Biol. 2007. PMID: 17030606 Free PMC article.

9

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation--relevance in a mouse model of Parkinson's disease.

Thomas T, Timmer M, Cesnulevicius K, Hitti E, Kotlyarov A, Gaestel M. Thomas T, et al. Among authors: gaestel m. J Neurochem. 2008 Jun;105(5):2039-52. doi: 10.1111/j.1471-4159.2008.05310.x. Epub 2008 Feb 22. J Neurochem. 2008. PMID: 18298661 Free article.

10

MK2 and MK3--a pair of isoenzymes?

Ronkina N, Kotlyarov A, Gaestel M. Ronkina N, et al. Among authors: gaestel m. Front Biosci. 2008 May 1;13:5511-21. doi: 10.2741/3095. Front Biosci. 2008. PMID: 18508601 Review.

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