Guenard D - Search Results

1

New potent acetylcholinesterase inhibitors in the tetracyclic triterpene series.

Sauvaître T, Barlier M, Herlem D, Gresh N, Chiaroni A, Guenard D, Guillou C. Sauvaître T, et al. Among authors: guenard d. J Med Chem. 2007 Nov 1;50(22):5311-23. doi: 10.1021/jm070536w. Epub 2007 Sep 29. J Med Chem. 2007. PMID: 17902635

2

Synthesis and biological evaluation of B-ring analogues of (-)-rhazinilam.

Décor A, Monse B, Martin MT, Chiaroni A, Thoret S, Guénard D, Guéritte F, Baudoin O. Décor A, et al. Among authors: guenard d. Bioorg Med Chem. 2006 Apr 1;14(7):2314-32. doi: 10.1016/j.bmc.2005.11.011. Epub 2005 Nov 28. Bioorg Med Chem. 2006. PMID: 16314101

3

Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives.

Larroque AL, Dubois J, Thoret S, Aubert G, Chiaroni A, Guéritte F, Guénard D. Larroque AL, et al. Among authors: guenard d. Bioorg Med Chem. 2007 Jan 1;15(1):563-74. doi: 10.1016/j.bmc.2006.09.030. Epub 2006 Oct 24. Bioorg Med Chem. 2007. PMID: 17064914

4

Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity.

Querolle O, Dubois J, Thoret S, Roussi F, Guéritte F, Guénard D. Querolle O, et al. Among authors: guenard d. J Med Chem. 2004 Nov 18;47(24):5937-44. doi: 10.1021/jm0497996. J Med Chem. 2004. PMID: 15537348

5

The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design.

Greenblatt HM, Guillou C, Guénard D, Argaman A, Botti S, Badet B, Thal C, Silman I, Sussman JL. Greenblatt HM, et al. Among authors: guenard d. J Am Chem Soc. 2004 Dec 1;126(47):15405-11. doi: 10.1021/ja0466154. J Am Chem Soc. 2004. PMID: 15563167

6

Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3'.

Larroque AL, Dubois J, Thoret S, Aubert G, Guénard D, Guéritte F. Larroque AL, et al. Among authors: guenard d. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4722-6. doi: 10.1016/j.bmcl.2005.07.069. Bioorg Med Chem Lett. 2005. PMID: 16165352

7

D-ring substituted rhazinilam analogues: semisynthesis and evaluation of antitubulin activity.

Dupont C, Guénard D, Tchertanov L, Thoret S, Guéritte F. Dupont C, et al. Among authors: guenard d. Bioorg Med Chem. 1999 Dec;7(12):2961-9. doi: 10.1016/s0968-0896(99)00241-2. Bioorg Med Chem. 1999. PMID: 10658602

8

Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity.

Querolle O, Dubois J, Thoret S, Roussi F, Montiel-Smith S, Guéritte F, Guénard D. Querolle O, et al. Among authors: guenard d. J Med Chem. 2003 Aug 14;46(17):3623-30. doi: 10.1021/jm030770w. J Med Chem. 2003. PMID: 12904066

9

Synthesis and biological evaluation of vinca alkaloids and phomopsin hybrids.

Ngo QA, Roussi F, Cormier A, Thoret S, Knossow M, Guénard D, Guéritte F. Ngo QA, et al. Among authors: guenard d. J Med Chem. 2009 Jan 8;52(1):134-42. doi: 10.1021/jm801064y. J Med Chem. 2009. PMID: 19072542

10

Relationships between the structure of taxol analogues and their antimitotic activity.

Guéritte-Voegelein F, Guénard D, Lavelle F, Le Goff MT, Mangatal L, Potier P. Guéritte-Voegelein F, et al. Among authors: guenard d. J Med Chem. 1991 Mar;34(3):992-8. doi: 10.1021/jm00107a017. J Med Chem. 1991. PMID: 1672159

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