Kehoe PG - Search Results

1

Immunocapture-based fluorometric assay for the measurement of neprilysin-specific enzyme activity in brain tissue homogenates and cerebrospinal fluid.

Miners JS, Verbeek MM, Rikkert MO, Kehoe PG, Love S. Miners JS, et al. Among authors: kehoe pg. J Neurosci Methods. 2008 Jan 30;167(2):229-36. doi: 10.1016/j.jneumeth.2007.08.012. Epub 2007 Aug 25. J Neurosci Methods. 2008. PMID: 17904641

2

Decreased expression and activity of neprilysin in Alzheimer disease are associated with cerebral amyloid angiopathy.

Miners JS, Van Helmond Z, Chalmers K, Wilcock G, Love S, Kehoe PG. Miners JS, et al. Among authors: kehoe pg. J Neuropathol Exp Neurol. 2006 Oct;65(10):1012-21. doi: 10.1097/01.jnen.0000240463.87886.9a. J Neuropathol Exp Neurol. 2006. PMID: 17021406

3

Immunocapture-based fluorometric assay for the measurement of insulin-degrading enzyme activity in brain tissue homogenates.

Miners JS, Kehoe PG, Love S. Miners JS, et al. Among authors: kehoe pg. J Neurosci Methods. 2008 Mar 30;169(1):177-81. doi: 10.1016/j.jneumeth.2007.12.003. Epub 2007 Dec 17. J Neurosci Methods. 2008. PMID: 18221786

4

Insights into the pathogenesis and pathogenicity of cerebral amyloid angiopathy.

Love S, Miners S, Palmer J, Chalmers K, Kehoe P. Love S, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14(12):4778-92. doi: 10.2741/3567. Front Biosci (Landmark Ed). 2009. PMID: 19273389 Free article. Review.

5

Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

Miners JS, Baig S, Tayler H, Kehoe PG, Love S. Miners JS, et al. Among authors: kehoe pg. J Neuropathol Exp Neurol. 2009 Aug;68(8):902-14. doi: 10.1097/NEN.0b013e3181afe475. J Neuropathol Exp Neurol. 2009. PMID: 19606063

6

CSF biomarker utilisation and ethical considerations of biomarker assisted diagnosis and research in dementia: perspectives from within the European Alzheimer's Disease Consortium (EADC).

Slats D, Spies PE, Sjögren MJ, Visser PJ, Verbeek MM, Rikkert MG, Kehoe PG. Slats D, et al. Among authors: kehoe pg. J Neurol Neurosurg Psychiatry. 2010 Jan;81(1):124-5. doi: 10.1136/jnnp.2009.176412. J Neurol Neurosurg Psychiatry. 2010. PMID: 20019235 No abstract available.

7

Accumulation of insoluble amyloid-β in down's syndrome is associated with increased BACE-1 and neprilysin activities.

Miners JS, Morris S, Love S, Kehoe PG. Miners JS, et al. Among authors: kehoe pg. J Alzheimers Dis. 2011;23(1):101-8. doi: 10.3233/JAD-2010-101395. J Alzheimers Dis. 2011. PMID: 20930275

8

Neprilysin protects against cerebral amyloid angiopathy and Aβ-induced degeneration of cerebrovascular smooth muscle cells.

Miners JS, Kehoe P, Love S. Miners JS, et al. Brain Pathol. 2011 Sep;21(5):594-605. doi: 10.1111/j.1750-3639.2011.00486.x. Epub 2011 Apr 3. Brain Pathol. 2011. PMID: 21382117 Free PMC article.

9

Aβ-degrading enzymes: potential for treatment of Alzheimer disease.

Miners JS, Barua N, Kehoe PG, Gill S, Love S. Miners JS, et al. Among authors: kehoe pg. J Neuropathol Exp Neurol. 2011 Nov;70(11):944-59. doi: 10.1097/NEN.0b013e3182345e46. J Neuropathol Exp Neurol. 2011. PMID: 22002425 Review.

10

Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus.

Hamilton G, Killick R; Genetic and Environmental Risk for Alzheimer's Disease Consortium; Translational Genomics Research Institute Consortium; Lambert JC, Amouyel P; European Alzheimer Disease Initiative; Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R. Hamilton G, et al. Neurobiol Aging. 2012 Aug;33(8):1848.e1-13. doi: 10.1016/j.neurobiolaging.2012.02.005. Epub 2012 Mar 8. Neurobiol Aging. 2012. PMID: 22405046 Free PMC article.

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