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Page 1
The R1441C mutation of LRRK2 disrupts GTP hydrolysis.
Lewis PA, Greggio E, Beilina A, Jain S, Baker A, Cookson MR. Lewis PA, et al. Biochem Biophys Res Commun. 2007 Jun 8;357(3):668-71. doi: 10.1016/j.bbrc.2007.04.006. Epub 2007 Apr 10. Biochem Biophys Res Commun. 2007. PMID: 17442267 Free PMC article.
Genetic neuropathology of Parkinson's disease.
Cookson MR, Hardy J, Lewis PA. Cookson MR, et al. Among authors: lewis pa. Int J Clin Exp Pathol. 2008 Jan 1;1(3):217-31. Int J Clin Exp Pathol. 2008. PMID: 18784814 Free PMC article.
Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue.
Devine MJ, Kaganovich A, Ryten M, Mamais A, Trabzuni D, Manzoni C, McGoldrick P, Chan D, Dillman A, Zerle J, Horan S, Taanman JW, Hardy J, Marti-Masso JF, Healy D, Schapira AH, Wolozin B, Bandopadhyay R, Cookson MR, van der Brug MP, Lewis PA. Devine MJ, et al. Among authors: lewis pa. PLoS One. 2011;6(7):e22489. doi: 10.1371/journal.pone.0022489. Epub 2011 Jul 22. PLoS One. 2011. PMID: 21799870 Free PMC article.
Gene expression in the Parkinson's disease brain.
Lewis PA, Cookson MR. Lewis PA, et al. Brain Res Bull. 2012 Jul 1;88(4):302-12. doi: 10.1016/j.brainresbull.2011.11.016. Epub 2011 Dec 3. Brain Res Bull. 2012. PMID: 22173063 Free PMC article. Review.
Parkinson's disease: From human genetics to clinical trials.
van der Brug MP, Singleton A, Gasser T, Lewis PA. van der Brug MP, et al. Among authors: lewis pa. Sci Transl Med. 2015 Sep 16;7(305):205ps20. doi: 10.1126/scitranslmed.aaa8280. Sci Transl Med. 2015. PMID: 26378242 Free PMC article.
The LRRK2 signalling system.
Price A, Manzoni C, Cookson MR, Lewis PA. Price A, et al. Among authors: lewis pa. Cell Tissue Res. 2018 Jul;373(1):39-50. doi: 10.1007/s00441-017-2759-9. Epub 2018 Jan 8. Cell Tissue Res. 2018. PMID: 29308544 Free PMC article. Review.
374 results