Lamba V - Search Results

1

Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression.

Lamba J, Lamba V, Strom S, Venkataramanan R, Schuetz E. Lamba J, et al. Among authors: lamba v. Drug Metab Dispos. 2008 Jan;36(1):169-81. doi: 10.1124/dmd.107.016600. Epub 2007 Oct 9. Drug Metab Dispos. 2008. PMID: 17925385

2

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.

Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG. Lamba V, et al. Among authors: lamba jk. Toxicol Appl Pharmacol. 2004 Sep 15;199(3):251-65. doi: 10.1016/j.taap.2003.12.027. Toxicol Appl Pharmacol. 2004. PMID: 15364541

3

Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics.

Lamba J, Lamba V, Schuetz E. Lamba J, et al. Among authors: lamba v. Curr Drug Metab. 2005 Aug;6(4):369-83. doi: 10.2174/1389200054633880. Curr Drug Metab. 2005. PMID: 16101575 Review.

4

MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.

Lamba J, Strom S, Venkataramanan R, Thummel KE, Lin YS, Liu W, Cheng C, Lamba V, Watkins PB, Schuetz E. Lamba J, et al. Among authors: lamba v. Clin Pharmacol Ther. 2006 Apr;79(4):325-38. doi: 10.1016/j.clpt.2005.11.013. Epub 2006 Feb 20. Clin Pharmacol Ther. 2006. PMID: 16580901

5

Genetic predictors of interindividual variability in hepatic CYP3A4 expression.

Lamba V, Panetta JC, Strom S, Schuetz EG. Lamba V, et al. J Pharmacol Exp Ther. 2010 Mar;332(3):1088-99. doi: 10.1124/jpet.109.160804. Epub 2009 Nov 24. J Pharmacol Exp Ther. 2010. PMID: 19934400 Free PMC article.

6

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.

Lamba V, Lamba J, Yasuda K, Strom S, Davila J, Hancock ML, Fackenthal JD, Rogan PK, Ring B, Wrighton SA, Schuetz EG. Lamba V, et al. Among authors: lamba j. J Pharmacol Exp Ther. 2003 Dec;307(3):906-22. doi: 10.1124/jpet.103.054866. Epub 2003 Oct 9. J Pharmacol Exp Ther. 2003. PMID: 14551287

7

ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics.

Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E. Finkelstein D, et al. Among authors: lamba v. Xenobiotica. 2006 Oct-Nov;36(10-11):989-1012. doi: 10.1080/00498250600861769. Xenobiotica. 2006. PMID: 17118917

8

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, Gonzalez FJ, Schuetz EG, Kim RB. Tirona RG, et al. Among authors: lamba v. Nat Med. 2003 Feb;9(2):220-4. doi: 10.1038/nm815. Epub 2003 Jan 6. Nat Med. 2003. PMID: 12514743

9

Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences.

Lamba JK, Lamba V, Yasuda K, Lin YS, Assem M, Thompson E, Strom S, Schuetz E. Lamba JK, et al. Among authors: lamba v. J Pharmacol Exp Ther. 2004 Nov;311(2):811-21. doi: 10.1124/jpet.104.069310. Epub 2004 Jun 11. J Pharmacol Exp Ther. 2004. PMID: 15194709

10

Pharmacogenetic pathway analysis of docetaxel elimination.

Baker SD, Verweij J, Cusatis GA, van Schaik RH, Marsh S, Orwick SJ, Franke RM, Hu S, Schuetz EG, Lamba V, Messersmith WA, Wolff AC, Carducci MA, Sparreboom A. Baker SD, et al. Among authors: lamba v. Clin Pharmacol Ther. 2009 Feb;85(2):155-63. doi: 10.1038/clpt.2008.95. Epub 2008 May 28. Clin Pharmacol Ther. 2009. PMID: 18509327 Free PMC article.

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