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MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.
Lloyd C, Freskgård PO, Newton P, Lowne D, Nickson A, Bogstedt A, Eketjäll S, Höglund K, Gustavsson S, Welsh F, Chessell T, McFarlane M, Bhat RV, Turner R, Perkinton MS, Santisteban Valencia Z, Lindqvist E, Pomfret M, Dudley AD, Vaughan TJ, Groves MT, Natanegara F, Feng Y, Sims JR, Proctor NK, Dage JL, Shering C, Tan K, Ostenfeld T, Billinton A, Chessell IP. Lloyd C, et al. Among authors: mcfarlane m. Alzheimers Dement. 2024 Nov;20(11):7762-7776. doi: 10.1002/alz.14238. Epub 2024 Sep 25. Alzheimers Dement. 2024. PMID: 39319998 Free PMC article.
Cannabis Use in Patients Seen in an Academic Radiation Oncology Department.
Cousins MM, Mayo C, Devasia T, Dykstra M, Regan S, Miller S, Allen SG, Bryant AK, Morales-Rivera K, Herr DJ, Edwards DM, Takayesu J, Birer S, Egerer N, Evans J, Elliott D, Henderson C, Laucis AM, McFarlane M, Dragovic AF, Shah J, Hayman JA, Coughlin LN, Ilgen M, Jagsi R. Cousins MM, et al. Among authors: mcfarlane m. Pract Radiat Oncol. 2023 Mar-Apr;13(2):112-121. doi: 10.1016/j.prro.2022.11.002. Epub 2022 Nov 30. Pract Radiat Oncol. 2023. PMID: 36460181 Free PMC article.
Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305.
Kinneer K, Wortmann P, Cooper ZA, Dickinson NJ, Masterson L, Cailleau T, Hutchinson I, Vijayakrishnan B, McFarlane M, Ball K, Davies M, Lewis A, Huang Y, Rosenbaum AI, Yuan J, Chesebrough J, Anderton J, Monks N, Novick S, Wang J, Dimasi N, Christie RJ, Sabol D, Tosto FA, Wallez Y, Leo E, Albertella MR, Staniszewska AD, Tice DA, Howard PW, Luheshi N, Sapra P. Kinneer K, et al. Among authors: mcfarlane m. Clin Cancer Res. 2023 Mar 14;29(6):1086-1101. doi: 10.1158/1078-0432.CCR-22-2630. Clin Cancer Res. 2023. PMID: 36355054
Nutrition in decompensated liver disease: A regional trainee-led audit investigating patient nutrition and outcomes following admission with decompensated chronic liver disease.
Morgan JA, O'Flynn L, Mahgoub S, McFarlane M, Burch N, Gordon V; West Midlands Research in Gastroenterology (WMRIG). Morgan JA, et al. Among authors: mcfarlane m. Clin Nutr ESPEN. 2022 Oct;51:185-189. doi: 10.1016/j.clnesp.2022.09.006. Epub 2022 Sep 10. Clin Nutr ESPEN. 2022. PMID: 36184203
Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody-Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer.
Gregson SJ, Pugh K, Patel N, Afif-Rider S, Vijayakrishnan B, Santos K, Riedl J, Hutchinson I, Kang GD, Chooi KP, Beard R, Adams L, Barry CS, Ball K, Masterson LA, McFarlane M, Hartley JA, Howard PW. Gregson SJ, et al. Among authors: mcfarlane m. Mol Cancer Ther. 2022 Sep 6;21(9):1439-1448. doi: 10.1158/1535-7163.MCT-22-0145. Mol Cancer Ther. 2022. PMID: 35793464
273 results