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Apolipoprotein E plays crucial roles in maintaining bone mass by promoting osteoblast differentiation via ERK1/2 pathway and by suppressing osteoclast differentiation via c-Fos, NFATc1, and NF-κB pathway.
Noguchi T, Ebina K, Hirao M, Otsuru S, Guess AJ, Kawase R, Ohama T, Yamashita S, Etani Y, Okamura G, Yoshikawa H. Noguchi T, et al. Among authors: yoshikawa h. Biochem Biophys Res Commun. 2018 Sep 5;503(2):644-650. doi: 10.1016/j.bbrc.2018.06.055. Epub 2018 Jun 15. Biochem Biophys Res Commun. 2018. PMID: 29906458
Assessment of effects of rhBMP-2 on interbody fusion with a novel rat model.
Okada R, Kaito T, Ishiguro H, Kushioka J, Otsuru S, Kanayama S, Bal Z, Kitaguchi K, Hashimoto K, Makino T, Takenaka S, Sakai Y, Yoshikawa H. Okada R, et al. Among authors: yoshikawa h. Spine J. 2020 May;20(5):821-829. doi: 10.1016/j.spinee.2019.12.014. Epub 2019 Dec 31. Spine J. 2020. PMID: 31901554
Modeling and remodeling effects of intermittent administration of teriparatide (parathyroid hormone 1-34) on bone morphogenetic protein-induced bone in a rat spinal fusion model.
Kaito T, Morimoto T, Kanayama S, Otsuru S, Kashii M, Makino T, Kitaguchi K, Furuya M, Chijimatsu R, Ebina K, Yoshikawa H. Kaito T, et al. Among authors: yoshikawa h. Bone Rep. 2016 Jul 16;5:173-180. doi: 10.1016/j.bonr.2016.07.003. eCollection 2016 Dec. Bone Rep. 2016. PMID: 28580385 Free PMC article.
Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model.
Ishiguro H, Kaito T, Yarimitsu S, Hashimoto K, Okada R, Kushioka J, Chijimatsu R, Takenaka S, Makino T, Sakai Y, Moriguchi Y, Otsuru S, Hart DA, Fujie H, Nakamura N, Yoshikawa H. Ishiguro H, et al. Among authors: yoshikawa h. Acta Biomater. 2019 Mar 15;87:118-129. doi: 10.1016/j.actbio.2019.01.050. Epub 2019 Jan 25. Acta Biomater. 2019. PMID: 30690206
3,182 results