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Missense mutations in the TGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes. Mutation in brief no. 982. Online.
Porzio O, Massa O, Cunsolo V, Colombo C, Malaponti M, Bertuzzi F, Hansen T, Johansen A, Pedersen O, Meschi F, Terrinoni A, Melino G, Federici M, Decarlo N, Menicagli M, Campani D, Marchetti P, Ferdaoussi M, Froguel P, Federici G, Vaxillaire M, Barbetti F. Porzio O, et al. Among authors: marchetti p. Hum Mutat. 2007 Nov;28(11):1150. doi: 10.1002/humu.9511. Hum Mutat. 2007. PMID: 17939176
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program.
Federici M, Hribal M, Perego L, Ranalli M, Caradonna Z, Perego C, Usellini L, Nano R, Bonini P, Bertuzzi F, Marlier LN, Davalli AM, Carandente O, Pontiroli AE, Melino G, Marchetti P, Lauro R, Sesti G, Folli F. Federici M, et al. Among authors: marchetti p. Diabetes. 2001 Jun;50(6):1290-301. doi: 10.2337/diabetes.50.6.1290. Diabetes. 2001. PMID: 11375329
NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro.
Pierucci D, Cicconi S, Bonini P, Ferrelli F, Pastore D, Matteucci C, Marselli L, Marchetti P, Ris F, Halban P, Oberholzer J, Federici M, Cozzolino F, Lauro R, Borboni P, Marlier LN. Pierucci D, et al. Among authors: marchetti p. Diabetologia. 2001 Oct;44(10):1281-95. doi: 10.1007/s001250100650. Diabetologia. 2001. PMID: 11692177
Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.
D'Alessandris C, Andreozzi F, Federici M, Cardellini M, Brunetti A, Ranalli M, Del Guerra S, Lauro D, Del Prato S, Marchetti P, Lauro R, Sesti G. D'Alessandris C, et al. Among authors: marchetti p. FASEB J. 2004 Jun;18(9):959-61. doi: 10.1096/fj.03-0725fje. Epub 2004 Apr 1. FASEB J. 2004. PMID: 15059979
Loss-of-Function Mutations in APPL1 in Familial Diabetes Mellitus.
Prudente S, Jungtrakoon P, Marucci A, Ludovico O, Buranasupkajorn P, Mazza T, Hastings T, Milano T, Morini E, Mercuri L, Bailetti D, Mendonca C, Alberico F, Basile G, Romani M, Miccinilli E, Pizzuti A, Carella M, Barbetti F, Pascarella S, Marchetti P, Trischitta V, Di Paola R, Doria A. Prudente S, et al. Among authors: marchetti p. Am J Hum Genet. 2015 Jul 2;97(1):177-85. doi: 10.1016/j.ajhg.2015.05.011. Epub 2015 Jun 11. Am J Hum Genet. 2015. PMID: 26073777 Free PMC article.
Hepatitis C virus infection and human pancreatic beta-cell dysfunction.
Masini M, Campani D, Boggi U, Menicagli M, Funel N, Pollera M, Lupi R, Del Guerra S, Bugliani M, Torri S, Del Prato S, Mosca F, Filipponi F, Marchetti P. Masini M, et al. Among authors: marchetti p. Diabetes Care. 2005 Apr;28(4):940-1. doi: 10.2337/diacare.28.4.940. Diabetes Care. 2005. PMID: 15793203 No abstract available.
Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.
Dotta F, Censini S, van Halteren AG, Marselli L, Masini M, Dionisi S, Mosca F, Boggi U, Muda AO, Del Prato S, Elliott JF, Covacci A, Rappuoli R, Roep BO, Marchetti P. Dotta F, et al. Among authors: marchetti p. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5115-20. doi: 10.1073/pnas.0700442104. Epub 2007 Mar 14. Proc Natl Acad Sci U S A. 2007. PMID: 17360338 Free PMC article.
The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.
Prudente S, Scarpelli D, Chandalia M, Zhang YY, Morini E, Del Guerra S, Perticone F, Li R, Powers C, Andreozzi F, Marchetti P, Dallapiccola B, Abate N, Doria A, Sesti G, Trischitta V. Prudente S, et al. Among authors: marchetti p. J Clin Endocrinol Metab. 2009 Jan;94(1):190-6. doi: 10.1210/jc.2008-1365. Epub 2008 Nov 4. J Clin Endocrinol Metab. 2009. PMID: 18984671 Free PMC article.
1,468 results