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Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens.
Shiryaev SA, Remacle AG, Ratnikov BI, Nelson NA, Savinov AY, Wei G, Bottini M, Rega MF, Parent A, Desjardins R, Fugere M, Day R, Sabet M, Pellecchia M, Liddington RC, Smith JW, Mustelin T, Guiney DG, Lebl M, Strongin AY. Shiryaev SA, et al. Among authors: liddington rc. J Biol Chem. 2007 Jul 20;282(29):20847-53. doi: 10.1074/jbc.M703847200. Epub 2007 May 30. J Biol Chem. 2007. PMID: 17537721 Free article.
Structure-based design of covalent Siah inhibitors.
Stebbins JL, Santelli E, Feng Y, De SK, Purves A, Motamedchaboki K, Wu B, Ronai ZA, Liddington RC, Pellecchia M. Stebbins JL, et al. Among authors: liddington rc. Chem Biol. 2013 Aug 22;20(8):973-82. doi: 10.1016/j.chembiol.2013.06.008. Epub 2013 Jul 25. Chem Biol. 2013. PMID: 23891150 Free PMC article.
148 results