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Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling.
Liotta F, Angeli R, Cosmi L, Filì L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F. Liotta F, et al. Among authors: santarlasci v. Stem Cells. 2008 Jan;26(1):279-89. doi: 10.1634/stemcells.2007-0454. Epub 2007 Oct 25. Stem Cells. 2008. PMID: 17962701
Phenotypic and functional features of human Th17 cells.
Annunziato F, Cosmi L, Santarlasci V, Maggi L, Liotta F, Mazzinghi B, Parente E, Filì L, Ferri S, Frosali F, Giudici F, Romagnani P, Parronchi P, Tonelli F, Maggi E, Romagnani S. Annunziato F, et al. Among authors: santarlasci v. J Exp Med. 2007 Aug 6;204(8):1849-61. doi: 10.1084/jem.20070663. Epub 2007 Jul 16. J Exp Med. 2007. PMID: 17635957 Free PMC article.
Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction.
Liotta F, Frosali F, Querci V, Mantei A, Filì L, Maggi L, Mazzinghi B, Angeli R, Ronconi E, Santarlasci V, Biagioli T, Lasagni L, Ballerini C, Parronchi P, Scheffold A, Cosmi L, Maggi E, Romagnani S, Annunziato F. Liotta F, et al. Among authors: santarlasci v. J Allergy Clin Immunol. 2008 Apr;121(4):1000-5.e8. doi: 10.1016/j.jaci.2008.01.004. Epub 2008 Mar 4. J Allergy Clin Immunol. 2008. PMID: 18313135
Mesenchymal stem cells are enriched in head neck squamous cell carcinoma, correlates with tumour size and inhibit T-cell proliferation.
Liotta F, Querci V, Mannelli G, Santarlasci V, Maggi L, Capone M, Rossi MC, Mazzoni A, Cosmi L, Romagnani S, Maggi E, Gallo O, Annunziato F. Liotta F, et al. Among authors: santarlasci v. Br J Cancer. 2015 Feb 17;112(4):745-54. doi: 10.1038/bjc.2015.15. Epub 2015 Feb 3. Br J Cancer. 2015. PMID: 25647013 Free PMC article.
Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines.
Cosmi L, Liotta F, Angeli R, Mazzinghi B, Santarlasci V, Manetti R, Lasagni L, Vanini V, Romagnani P, Maggi E, Annunziato F, Romagnani S. Cosmi L, et al. Among authors: santarlasci v. Blood. 2004 Apr 15;103(8):3117-21. doi: 10.1182/blood-2003-09-3302. Epub 2003 Dec 24. Blood. 2004. PMID: 15070693 Free article.
Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor.
Cosmi L, De Palma R, Santarlasci V, Maggi L, Capone M, Frosali F, Rodolico G, Querci V, Abbate G, Angeli R, Berrino L, Fambrini M, Caproni M, Tonelli F, Lazzeri E, Parronchi P, Liotta F, Maggi E, Romagnani S, Annunziato F. Cosmi L, et al. Among authors: santarlasci v. J Exp Med. 2008 Aug 4;205(8):1903-16. doi: 10.1084/jem.20080397. Epub 2008 Jul 28. J Exp Med. 2008. PMID: 18663128 Free PMC article.
42 results