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Mimicking gene defects to treat drug dependence.
Sellers EM, Tyndale RF. Sellers EM, et al. Among authors: tyndale rf. Ann N Y Acad Sci. 2000;909:233-46. doi: 10.1111/j.1749-6632.2000.tb06685.x. Ann N Y Acad Sci. 2000. PMID: 10911933 Review.
A common genetic defect in nicotine metabolism decreases risk for dependence and lowers cigarette consumption.
Tyndale RF, Pianezza ML, Sellers EM. Tyndale RF, et al. Nicotine Tob Res. 1999;1 Suppl 2:S63-7; discussion S69-70. doi: 10.1080/14622299050011831. Nicotine Tob Res. 1999. PMID: 11768189 Review.
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if dependent, how impairment of the CYP2A6 gene function decreases the number of cigarettes consumed by smokers (Pianezza M, Sellers EM, Tyndale …
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if depend …
446 results