Ambudkar SV - Search Results

1

ABC drug transporters as molecular targets for the prevention of multidrug resistance and drug-drug interactions.

Calcagno AM, Kim IW, Wu CP, Shukla S, Ambudkar SV. Calcagno AM, et al. Among authors: ambudkar sv. Curr Drug Deliv. 2007 Oct;4(4):324-33. doi: 10.2174/156720107782151241. Curr Drug Deliv. 2007. PMID: 17979652 Review.

2

P-glycoprotein and multidrug resistance.

Gottesman MM, Pastan I, Ambudkar SV. Gottesman MM, et al. Among authors: ambudkar sv. Curr Opin Genet Dev. 1996 Oct;6(5):610-7. doi: 10.1016/s0959-437x(96)80091-8. Curr Opin Genet Dev. 1996. PMID: 8939727 Review.

3

Biochemical, cellular, and pharmacological aspects of the multidrug transporter.

Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Ambudkar SV, et al. Annu Rev Pharmacol Toxicol. 1999;39:361-98. doi: 10.1146/annurev.pharmtox.39.1.361. Annu Rev Pharmacol Toxicol. 1999. PMID: 10331089 Review.

4

Overview: ABC transporters and human disease.

Gottesman MM, Ambudkar SV. Gottesman MM, et al. Among authors: ambudkar sv. J Bioenerg Biomembr. 2001 Dec;33(6):453-8. doi: 10.1023/a:1012866803188. J Bioenerg Biomembr. 2001. PMID: 11804186 Review.

5

The mechanism of action of multidrug-resistance-linked P-glycoprotein.

Sauna ZE, Smith MM, Müller M, Kerr KM, Ambudkar SV. Sauna ZE, et al. Among authors: ambudkar sv. J Bioenerg Biomembr. 2001 Dec;33(6):481-91. doi: 10.1023/a:1012875105006. J Bioenerg Biomembr. 2001. PMID: 11804190 Review.

6

P-glycoprotein: from genomics to mechanism.

Ambudkar SV, Kimchi-Sarfaty C, Sauna ZE, Gottesman MM. Ambudkar SV, et al. Oncogene. 2003 Oct 20;22(47):7468-85. doi: 10.1038/sj.onc.1206948. Oncogene. 2003. PMID: 14576852 Review.

7

Functional characterization of Candida albicans ABC transporter Cdr1p.

Shukla S, Saini P, Smriti, Jha S, Ambudkar SV, Prasad R. Shukla S, et al. Among authors: ambudkar sv. Eukaryot Cell. 2003 Dec;2(6):1361-75. doi: 10.1128/EC.2.6.1361-1375.2003. Eukaryot Cell. 2003. PMID: 14665469 Free PMC article.

8

The molecular basis of the action of disulfiram as a modulator of the multidrug resistance-linked ATP binding cassette transporters MDR1 (ABCB1) and MRP1 (ABCC1).

Sauna ZE, Peng XH, Nandigama K, Tekle S, Ambudkar SV. Sauna ZE, et al. Among authors: ambudkar sv. Mol Pharmacol. 2004 Mar;65(3):675-84. doi: 10.1124/mol.65.3.675. Mol Pharmacol. 2004. PMID: 14978246

9

Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520.

Shukla S, Ambudkar SV, Prasad R. Shukla S, et al. Among authors: ambudkar sv. J Antimicrob Chemother. 2004 Jul;54(1):38-45. doi: 10.1093/jac/dkh308. Epub 2004 Jun 9. J Antimicrob Chemother. 2004. PMID: 15190023

10

Disulfiram is a potent modulator of multidrug transporter Cdr1p of Candida albicans.

Shukla S, Sauna ZE, Prasad R, Ambudkar SV. Shukla S, et al. Among authors: ambudkar sv. Biochem Biophys Res Commun. 2004 Sep 17;322(2):520-5. doi: 10.1016/j.bbrc.2004.07.151. Biochem Biophys Res Commun. 2004. PMID: 15325261

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