Singer A - Search Results

1

Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain.

Proudfoot M, Sanders SA, Singer A, Zhang R, Brown G, Binkowski A, Xu L, Lukin JA, Murzin AG, Joachimiak A, Arrowsmith CH, Edwards AM, Savchenko AV, Yakunin AF. Proudfoot M, et al. Among authors: singer a. J Mol Biol. 2008 Jan 4;375(1):301-15. doi: 10.1016/j.jmb.2007.10.060. Epub 2007 Nov 1. J Mol Biol. 2008. PMID: 18021800 Free PMC article.

2

Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.

Savchenko A, Proudfoot M, Skarina T, Singer A, Litvinova O, Sanishvili R, Brown G, Chirgadze N, Yakunin AF. Savchenko A, et al. Among authors: singer a. J Mol Biol. 2007 Dec 7;374(4):1091-103. doi: 10.1016/j.jmb.2007.10.012. Epub 2007 Oct 11. J Mol Biol. 2007. PMID: 17976651

3

Structural and biochemical characterization of the type II fructose-1,6-bisphosphatase GlpX from Escherichia coli.

Brown G, Singer A, Lunin VV, Proudfoot M, Skarina T, Flick R, Kochinyan S, Sanishvili R, Joachimiak A, Edwards AM, Savchenko A, Yakunin AF. Brown G, et al. Among authors: singer a. J Biol Chem. 2009 Feb 6;284(6):3784-92. doi: 10.1074/jbc.M808186200. Epub 2008 Dec 10. J Biol Chem. 2009. PMID: 19073594 Free PMC article.

4

Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases.

Tchigvintsev A, Xu X, Singer A, Chang C, Brown G, Proudfoot M, Cui H, Flick R, Anderson WF, Joachimiak A, Galperin MY, Savchenko A, Yakunin AF. Tchigvintsev A, et al. Among authors: singer a. J Mol Biol. 2010 Sep 24;402(3):524-38. doi: 10.1016/j.jmb.2010.07.050. Epub 2010 Aug 4. J Mol Biol. 2010. PMID: 20691189 Free PMC article.

5

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases.

Singer AU, Rohde JR, Lam R, Skarina T, Kagan O, Dileo R, Chirgadze NY, Cuff ME, Joachimiak A, Tyers M, Sansonetti PJ, Parsot C, Savchenko A. Singer AU, et al. Nat Struct Mol Biol. 2008 Dec;15(12):1293-301. doi: 10.1038/nsmb.1511. Epub 2008 Nov 9. Nat Struct Mol Biol. 2008. PMID: 18997778 Free PMC article.

6

Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.

Tchigvintsev A, Singer AU, Flick R, Petit P, Brown G, Evdokimova E, Savchenko A, Yakunin AF. Tchigvintsev A, et al. Among authors: singer au. Biochem J. 2011 Jul 15;437(2):243-53. doi: 10.1042/BJ20110304. Biochem J. 2011. PMID: 21548881 Free PMC article.

7

ADP-dependent 6-phosphofructokinase from Pyrococcus horikoshii OT3: structure determination and biochemical characterization of PH1645.

Currie MA, Merino F, Skarina T, Wong AH, Singer A, Brown G, Savchenko A, Caniuguir A, Guixé V, Yakunin AF, Jia Z. Currie MA, et al. Among authors: singer a. J Biol Chem. 2009 Aug 21;284(34):22664-71. doi: 10.1074/jbc.M109.012401. Epub 2009 Jun 24. J Biol Chem. 2009. PMID: 19553681 Free PMC article.

8

Structure and activity of the metal-independent fructose-1,6-bisphosphatase YK23 from Saccharomyces cerevisiae.

Kuznetsova E, Xu L, Singer A, Brown G, Dong A, Flick R, Cui H, Cuff M, Joachimiak A, Savchenko A, Yakunin AF. Kuznetsova E, et al. Among authors: singer a. J Biol Chem. 2010 Jul 2;285(27):21049-59. doi: 10.1074/jbc.M110.118315. Epub 2010 Apr 28. J Biol Chem. 2010. PMID: 20427268 Free PMC article.

9

Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.

Tchigvintsev A, Singer A, Brown G, Flick R, Evdokimova E, Tan K, Gonzalez CF, Savchenko A, Yakunin AF. Tchigvintsev A, et al. Among authors: singer a. J Biol Chem. 2012 Jan 13;287(3):1874-83. doi: 10.1074/jbc.M111.294561. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22128181 Free PMC article.

10

Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.

Brown G, Singer A, Proudfoot M, Skarina T, Kim Y, Chang C, Dementieva I, Kuznetsova E, Gonzalez CF, Joachimiak A, Savchenko A, Yakunin AF. Brown G, et al. Among authors: singer a. Biochemistry. 2008 May 27;47(21):5724-35. doi: 10.1021/bi800097h. Epub 2008 May 6. Biochemistry. 2008. PMID: 18459799 Free PMC article.

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