Zisterer DM - Search Results

1

Benzothiepin-derived molecular scaffolds for estrogen receptor modulators: synthesis and antagonistic effects in breast cancer cells.

Meegan MJ, Barrett I, Zimmermann J, Knox AJ, Zisterer DM, Lloyd DG. Meegan MJ, et al. Among authors: zisterer dm. J Enzyme Inhib Med Chem. 2007 Oct;22(5):655-66. doi: 10.1080/14756360701503232. J Enzyme Inhib Med Chem. 2007. PMID: 18035834 Free article.

2

Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. Among authors: zisterer dm. J Med Chem. 2001 Mar 29;44(7):1072-84. doi: 10.1021/jm001119l. J Med Chem. 2001. PMID: 11297454

3

Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. Among authors: zisterer dm. Anticancer Drug Des. 2001 Feb;16(1):57-69. Anticancer Drug Des. 2001. PMID: 11762645

4

Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.

Lloyd DG, Hughes RB, Zisterer DM, Williams DC, Fattorusso C, Catalanotti B, Campiani G, Meegan MJ. Lloyd DG, et al. Among authors: zisterer dm. J Med Chem. 2004 Nov 4;47(23):5612-5. doi: 10.1021/jm0495834. J Med Chem. 2004. PMID: 15509159

5

Pyrrolo[1,5]benzoxa(thia)zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target.

Mc Gee MM, Gemma S, Butini S, Ramunno A, Zisterer DM, Fattorusso C, Catalanotti B, Kukreja G, Fiorini I, Pisano C, Cucco C, Novellino E, Nacci V, Williams DC, Campiani G. Mc Gee MM, et al. Among authors: zisterer dm. J Med Chem. 2005 Jun 30;48(13):4367-77. doi: 10.1021/jm049402y. J Med Chem. 2005. PMID: 15974589

6

The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo.

Greene LM, Fleeton M, Mulligan J, Gowda C, Sheahan BJ, Atkins GJ, Campiani G, Nacci V, Lawler M, Williams DC, Zisterer DM. Greene LM, et al. Among authors: zisterer dm. Oncol Rep. 2005 Nov;14(5):1357-63. Oncol Rep. 2005. PMID: 16211309

7

Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor antagonists.

Lloyd DG, Smith HM, O'Sullivan T, Knox AS, Zisterer DM, Meegan MJ. Lloyd DG, et al. Among authors: zisterer dm. Med Chem. 2006 Mar;2(2):147-68. doi: 10.2174/157340606776056142. Med Chem. 2006. PMID: 16787364

8

Synthesis, structure-activity relationships and antagonistic effects in human MCF-7 breast cancer cells of flexible estrogen receptor modulators.

Lloyd DG, Smith HM, O'Sullivan T, Zisterer DM, Meegan MJ. Lloyd DG, et al. Among authors: zisterer dm. Med Chem. 2005 Jul;1(4):335-53. doi: 10.2174/1573406054368666. Med Chem. 2005. PMID: 16789891

9

Flexible estrogen receptor modulators: synthesis, biochemistry and molecular modeling studies for 3-benzyl-4,6-diarylhex-3-ene and 3,4,6-triarylhex-3-ene derivatives.

Smith HM, Knox AJ, Zisterer DM, Lloyd DG, Meegan MJ. Smith HM, et al. Among authors: zisterer dm. Med Chem. 2007 Mar;3(2):135-55. doi: 10.2174/157340607780059503. Med Chem. 2007. PMID: 17348852

10

Target specific virtual screening: optimization of an estrogen receptor screening platform.

Knox AJ, Meegan MJ, Sobolev V, Frost D, Zisterer DM, Williams DC, Lloyd DG. Knox AJ, et al. Among authors: zisterer dm. J Med Chem. 2007 Nov 1;50(22):5301-10. doi: 10.1021/jm0700262. Epub 2007 Oct 5. J Med Chem. 2007. PMID: 17918820

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