Araldi GL - Search Results

1

Synthesis and evaluation of a gamma-lactam as a highly selective EP2 and EP4 receptor agonist.

Xiao Y, Araldi GL, Zhao Z, Reddy A, Karra S, Brugger N, Fischer D, Palmer E, Bao B, McKenna SD. Xiao Y, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 2008 Jan 15;18(2):821-4. doi: 10.1016/j.bmcl.2007.11.020. Epub 2007 Nov 13. Bioorg Med Chem Lett. 2008. PMID: 18039575

2

Discovery of novel prostaglandin analogs of PGE2 as potent and selective EP2 and EP4 receptor agonists.

Xiao Y, Araldi GL, Zhao Z, Brugger N, Karra S, Fischer D, Palmer E. Xiao Y, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4323-7. doi: 10.1016/j.bmcl.2007.05.025. Epub 2007 May 16. Bioorg Med Chem Lett. 2007. PMID: 17531488

3

Synthesis and evaluation of novel pyrazolidinone analogs of PGE2 as EP2 and EP4 receptors agonists.

Zhao Z, Araldi GL, Xiao Y, Reddy AP, Liao Y, Karra S, Brugger N, Fischer D, Palmer E. Zhao Z, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6572-5. doi: 10.1016/j.bmcl.2007.09.074. Epub 2007 Sep 26. Bioorg Med Chem Lett. 2007. PMID: 17931866

4

Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species.

Brugger N, Kim NN, Araldi GL, Traish AM, Palmer SS. Brugger N, et al. Among authors: araldi gl. J Sex Med. 2008 Feb;5(2):344-56. doi: 10.1111/j.1743-6109.2007.00676.x. Epub 2007 Nov 28. J Sex Med. 2008. PMID: 18047485

5

Non-covalent thrombin inhibitors featuring P(3)-heterocycles with P(1)-monocyclic arginine surrogates.

Reiner JE, Siev DV, Araldi GL, Cui JJ, Ho JZ, Reddy KM, Mamedova L, Vu PH, Lee KS, Minami NK, Gibson TS, Anderson SM, Bradbury AE, Nolan TG, Semple JE. Reiner JE, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 2002 Apr 22;12(8):1203-8. doi: 10.1016/s0960-894x(02)00129-4. Bioorg Med Chem Lett. 2002. PMID: 11934589

6

Non-covalent thrombin inhibitors featuring P3-heterocycles with P1-bicyclic arginine surrogates.

Cui JJ, Araldi GL, Reiner JE, Reddy KM, Kemp SJ, Ho JZ, Siev DV, Mamedova L, Gibson TS, Gaudette JA, Minami NK, Anderson SM, Bradbury AE, Nolan TG, Semple JE. Cui JJ, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2925-30. doi: 10.1016/s0960-894x(02)00585-1. Bioorg Med Chem Lett. 2002. PMID: 12270176

7

Synthesis and metabotropic glutamate receptor activity of a 2-aminobicyclo[3.2.0]heptane-2,5-dicarboxylic acid, a molecule possessing an extended glutamate conformation.

Kozikowski AP, Araldi GL, Flippen-Anderson J, George C, Pshenichkin S, Surina E, Wroblewski J. Kozikowski AP, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 1998 Apr 21;8(8):925-30. doi: 10.1016/s0960-894x(98)00146-2. Bioorg Med Chem Lett. 1998. PMID: 9871513 Free article.

8

Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis.

Araldi GL, Hwang YW. Araldi GL, et al. Bioorg Med Chem Lett. 2022 May 15;64:128675. doi: 10.1016/j.bmcl.2022.128675. Epub 2022 Mar 12. Bioorg Med Chem Lett. 2022. PMID: 35292341 Free PMC article.

9

1-amino-APDC, a partial agonist of group II metabotropic glutamate receptors with neuroprotective properties.

Kozikowski AP, Araldi GL, Tückmantel W, Pshenichkin S, Surina E, Wroblewski JT. Kozikowski AP, et al. Among authors: araldi gl. Bioorg Med Chem Lett. 1999 Jun 21;9(12):1721-6. doi: 10.1016/s0960-894x(99)00266-8. Bioorg Med Chem Lett. 1999. PMID: 10397508 Free article.

10

Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid-I, a potent mGluR agonist.

Kozikowski AP, Steensma D, Araldi GL, Tückmantel W, Wang S, Pshenichkin S, Surina E, Wroblewski JT. Kozikowski AP, et al. Among authors: araldi gl. J Med Chem. 1998 May 7;41(10):1641-50. doi: 10.1021/jm970719q. J Med Chem. 1998. PMID: 9572889

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