Witt O - Search Results

1

Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.

Deubzer HE, Ehemann V, Westermann F, Heinrich R, Mechtersheimer G, Kulozik AE, Schwab M, Witt O. Deubzer HE, et al. Among authors: witt o. Int J Cancer. 2008 Apr 15;122(8):1891-900. doi: 10.1002/ijc.23295. Int J Cancer. 2008. PMID: 18074352

2

Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.

Deubzer H, Busche B, Rönndahl G, Eikel D, Michaelis M, Cinatl J, Schulze S, Nau H, Witt O. Deubzer H, et al. Among authors: witt o. Leuk Res. 2006 Sep;30(9):1167-75. doi: 10.1016/j.leukres.2006.01.009. Epub 2006 Feb 28. Leuk Res. 2006. PMID: 16510182

3

Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.

Deubzer HE, Ehemann V, Kulozik AE, Westermann F, Savelyeva L, Kopp-Schneider A, Riester D, Schwab M, Witt O. Deubzer HE, et al. Among authors: witt o. Cancer Lett. 2008 Jun 8;264(1):21-8. doi: 10.1016/j.canlet.2008.01.002. Epub 2008 Feb 8. Cancer Lett. 2008. PMID: 18262346

4

Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.

Wegener D, Hildmann C, Riester D, Schober A, Meyer-Almes FJ, Deubzer HE, Oehme I, Witt O, Lang S, Jaensch M, Makarov V, Lange C, Busse B, Schwienhorst A. Wegener D, et al. Among authors: witt o. Biochem J. 2008 Jul 1;413(1):143-50. doi: 10.1042/BJ20080536. Biochem J. 2008. PMID: 18384290

5

Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells.

Schulte JH, Kirfel J, Lim S, Schramm A, Friedrichs N, Deubzer HE, Witt O, Eggert A, Buettner R. Schulte JH, et al. Among authors: witt o. Cancer Lett. 2008 Nov 18;271(1):56-63. doi: 10.1016/j.canlet.2008.05.039. Epub 2008 Jul 11. Cancer Lett. 2008. PMID: 18620802

6

HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells.

Wegener D, Deubzer HE, Oehme I, Milde T, Hildmann C, Schwienhorst A, Witt O. Wegener D, et al. Among authors: witt o. Anticancer Drugs. 2008 Oct;19(9):849-57. doi: 10.1097/CAD.0b013e32830efbeb. Anticancer Drugs. 2008. PMID: 18765999

7

HDAC family: What are the cancer relevant targets?

Witt O, Deubzer HE, Milde T, Oehme I. Witt O, et al. Cancer Lett. 2009 May 8;277(1):8-21. doi: 10.1016/j.canlet.2008.08.016. Epub 2008 Sep 27. Cancer Lett. 2009. PMID: 18824292 Review.

8

Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins.

Michaelis M, Bliss J, Arnold SC, Hinsch N, Rothweiler F, Deubzer HE, Witt O, Langer K, Doerr HW, Wels WS, Cinatl J Jr. Michaelis M, et al. Among authors: witt o. Clin Cancer Res. 2008 Oct 15;14(20):6531-7. doi: 10.1158/1078-0432.CCR-08-0821. Clin Cancer Res. 2008. PMID: 18927293 Free article.

9

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.

Milde T, Pfister S, Korshunov A, Deubzer HE, Oehme I, Ernst A, Starzinski-Powitz A, Seitz A, Lichter P, von Deimling A, Witt O. Milde T, et al. Among authors: witt o. Genes Chromosomes Cancer. 2009 Mar;48(3):229-38. doi: 10.1002/gcc.20635. Genes Chromosomes Cancer. 2009. PMID: 19025795

10

Histone deacetylase 8 in neuroblastoma tumorigenesis.

Oehme I, Deubzer HE, Wegener D, Pickert D, Linke JP, Hero B, Kopp-Schneider A, Westermann F, Ulrich SM, von Deimling A, Fischer M, Witt O. Oehme I, et al. Among authors: witt o. Clin Cancer Res. 2009 Jan 1;15(1):91-9. doi: 10.1158/1078-0432.CCR-08-0684. Clin Cancer Res. 2009. PMID: 19118036

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