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Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa.
Winstanley C, Langille MG, Fothergill JL, Kukavica-Ibrulj I, Paradis-Bleau C, Sanschagrin F, Thomson NR, Winsor GL, Quail MA, Lennard N, Bignell A, Clarke L, Seeger K, Saunders D, Harris D, Parkhill J, Hancock RE, Brinkman FS, Levesque RC. Winstanley C, et al. Genome Res. 2009 Jan;19(1):12-23. doi: 10.1101/gr.086082.108. Epub 2008 Dec 1. Genome Res. 2009. PMID: 19047519 Free PMC article.
Comparative genomics of isolates of a Pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients.
Jeukens J, Boyle B, Kukavica-Ibrulj I, Ouellet MM, Aaron SD, Charette SJ, Fothergill JL, Tucker NP, Winstanley C, Levesque RC. Jeukens J, et al. Among authors: winstanley c. PLoS One. 2014 Feb 5;9(2):e87611. doi: 10.1371/journal.pone.0087611. eCollection 2014. PLoS One. 2014. PMID: 24505294 Free PMC article. Clinical Trial.
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium.
Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S, Maaroufi H, Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel É, Grimwood K, Hancock RE, Harrison JJ, Heeb S, Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S, Loman N, Malouin F, Manos J, McArthur AG, McKeown J, Milot J, Naghra H, Nguyen D, Pereira SK, Perron GG, Pirnay JP, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC. Freschi L, et al. Among authors: winstanley c. Front Microbiol. 2015 Sep 29;6:1036. doi: 10.3389/fmicb.2015.01036. eCollection 2015. Front Microbiol. 2015. PMID: 26483767 Free PMC article.
Temperate phages enhance pathogen fitness in chronic lung infection.
Davies EV, James CE, Kukavica-Ibrulj I, Levesque RC, Brockhurst MA, Winstanley C. Davies EV, et al. Among authors: winstanley c. ISME J. 2016 Oct;10(10):2553-5. doi: 10.1038/ismej.2016.51. Epub 2016 Apr 12. ISME J. 2016. PMID: 27070941 Free PMC article.
Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools.
Freschi L, Bertelli C, Jeukens J, Moore MP, Kukavica-Ibrulj I, Emond-Rheault JG, Hamel J, Fothergill JL, Tucker NP, McClean S, Klockgether J, de Soyza A, Brinkman FSL, Levesque RC, Winstanley C. Freschi L, et al. Among authors: winstanley c. FEMS Microbiol Lett. 2018 Jul 1;365(14). doi: 10.1093/femsle/fny120. FEMS Microbiol Lett. 2018. PMID: 29897457 Free article.
A megaplasmid family driving dissemination of multidrug resistance in Pseudomonas.
Cazares A, Moore MP, Hall JPJ, Wright LL, Grimes M, Emond-Rhéault JG, Pongchaikul P, Santanirand P, Levesque RC, Fothergill JL, Winstanley C. Cazares A, et al. Among authors: winstanley c. Nat Commun. 2020 Mar 13;11(1):1370. doi: 10.1038/s41467-020-15081-7. Nat Commun. 2020. PMID: 32170080 Free PMC article.
Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain.
Moore MP, Lamont IL, Williams D, Paterson S, Kukavica-Ibrulj I, Tucker NP, Kenna DTD, Turton JF, Jeukens J, Freschi L, Wee BA, Loman NJ, Holden S, Manzoor S, Hawkey P, Southern KW, Walshaw MJ, Levesque RC, Fothergill JL, Winstanley C. Moore MP, et al. Among authors: winstanley c. Microb Genom. 2021 Mar;7(3):mgen000511. doi: 10.1099/mgen.0.000511. Epub 2021 Mar 15. Microb Genom. 2021. PMID: 33720817 Free PMC article.
284 results