Clark PR - Search Results

1

Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect.

Clark PR, Pober JS, Kluger MS. Clark PR, et al. Nucleic Acids Res. 2008 Mar;36(4):1081-97. doi: 10.1093/nar/gkm630. Epub 2007 Dec 20. Nucleic Acids Res. 2008. PMID: 18096615 Free PMC article.

2

Increased ICAM-1 expression causes endothelial cell leakiness, cytoskeletal reorganization and junctional alterations.

Clark PR, Manes TD, Pober JS, Kluger MS. Clark PR, et al. J Invest Dermatol. 2007 Apr;127(4):762-74. doi: 10.1038/sj.jid.5700670. Epub 2006 Dec 28. J Invest Dermatol. 2007. PMID: 17195014 Free article.

3

MEK5 is activated by shear stress, activates ERK5 and induces KLF4 to modulate TNF responses in human dermal microvascular endothelial cells.

Clark PR, Jensen TJ, Kluger MS, Morelock M, Hanidu A, Qi Z, Tatake RJ, Pober JS. Clark PR, et al. Microcirculation. 2011 Feb;18(2):102-17. doi: 10.1111/j.1549-8719.2010.00071.x. Microcirculation. 2011. PMID: 21166929 Free PMC article.

4

Claudin-5 controls intercellular barriers of human dermal microvascular but not human umbilical vein endothelial cells.

Kluger MS, Clark PR, Tellides G, Gerke V, Pober JS. Kluger MS, et al. Among authors: clark pr. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):489-500. doi: 10.1161/ATVBAHA.112.300893. Epub 2013 Jan 3. Arterioscler Thromb Vasc Biol. 2013. PMID: 23288152 Free PMC article.

5

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases.

Clark PR, Kim RK, Pober JS, Kluger MS. Clark PR, et al. PLoS One. 2015 Mar 27;10(3):e0120075. doi: 10.1371/journal.pone.0120075. eCollection 2015. PLoS One. 2015. PMID: 25816133 Free PMC article.

6

Bone marrow stem cells contribute to repair of the ischemically injured renal tubule.

Kale S, Karihaloo A, Clark PR, Kashgarian M, Krause DS, Cantley LG. Kale S, et al. Among authors: clark pr. J Clin Invest. 2003 Jul;112(1):42-9. doi: 10.1172/JCI17856. Epub 2003 Jun 16. J Clin Invest. 2003. PMID: 12824456 Free PMC article.

7

RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq.

Ren P, Peng L, Yang L, Suzuki K, Fang Z, Renauer PA, Lin Q, Bai M, Li T, Clark P, Klein D, Chen S. Ren P, et al. Cell Chem Biol. 2023 Jan 19;30(1):85-96.e6. doi: 10.1016/j.chembiol.2022.12.005. Epub 2023 Jan 13. Cell Chem Biol. 2023. PMID: 36640761 Free PMC article.

8

Double knockout CRISPR screen for cancer resistance to T cell cytotoxicity.

Park JJ, Codina A, Ye L, Lam S, Guo J, Clark P, Zhou X, Peng L, Chen S. Park JJ, et al. J Hematol Oncol. 2022 Dec 1;15(1):172. doi: 10.1186/s13045-022-01389-y. J Hematol Oncol. 2022. PMID: 36456981 Free PMC article.

9

Immunogenetic Metabolomics Reveals Key Enzymes That Modulate CAR T-cell Metabolism and Function.

Renauer P, Park JJ, Bai M, Acosta A, Lee WH, Lin GH, Zhang Y, Dai X, Wang G, Errami Y, Wu T, Clark P, Ye L, Yang Q, Chen S. Renauer P, et al. Cancer Immunol Res. 2023 Aug 3;11(8):1068-1084. doi: 10.1158/2326-6066.CIR-22-0565. Cancer Immunol Res. 2023. PMID: 37253111 Free PMC article.

10

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade.

Wang G, Chow RD, Zhu L, Bai Z, Ye L, Zhang F, Renauer PA, Dong MB, Dai X, Zhang X, Du Y, Cheng Y, Niu L, Chu Z, Kim K, Liao C, Clark P, Errami Y, Chen S. Wang G, et al. Cancer Discov. 2020 Dec;10(12):1912-1933. doi: 10.1158/2159-8290.CD-19-1448. Epub 2020 Sep 4. Cancer Discov. 2020. PMID: 32887696 Free PMC article.

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