Kopan R - Search Results

1

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

Bai S, Kopan R, Zou W, Hilton MJ, Ong CT, Long F, Ross FP, Teitelbaum SL. Bai S, et al. Among authors: kopan r. J Biol Chem. 2008 Mar 7;283(10):6509-18. doi: 10.1074/jbc.M707000200. Epub 2007 Dec 22. J Biol Chem. 2008. PMID: 18156632 Free article.

2

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.

Hilton MJ, Tu X, Wu X, Bai S, Zhao H, Kobayashi T, Kronenberg HM, Teitelbaum SL, Ross FP, Kopan R, Long F. Hilton MJ, et al. Among authors: kopan r. Nat Med. 2008 Mar;14(3):306-14. doi: 10.1038/nm1716. Epub 2008 Feb 24. Nat Med. 2008. PMID: 18297083 Free PMC article.

3

Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.

Ong CT, Cheng HT, Chang LW, Ohtsuka T, Kageyama R, Stormo GD, Kopan R. Ong CT, et al. Among authors: kopan r. J Biol Chem. 2006 Feb 24;281(8):5106-19. doi: 10.1074/jbc.M506108200. Epub 2005 Dec 19. J Biol Chem. 2006. PMID: 16365048 Free article.

4

Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition.

Ong CT, Sedy JR, Murphy KM, Kopan R. Ong CT, et al. Among authors: kopan r. PLoS One. 2008 Jul 30;3(7):e2823. doi: 10.1371/journal.pone.0002823. PLoS One. 2008. PMID: 18665263 Free PMC article.

5

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.

Vooijs M, Ong CT, Hadland B, Huppert S, Liu Z, Korving J, van den Born M, Stappenbeck T, Wu Y, Clevers H, Kopan R. Vooijs M, et al. Among authors: kopan r. Development. 2007 Feb;134(3):535-44. doi: 10.1242/dev.02733. Development. 2007. PMID: 17215306 Free PMC article.

6

Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1.

Tu X, Chen J, Lim J, Karner CM, Lee SY, Heisig J, Wiese C, Surendran K, Kopan R, Gessler M, Long F. Tu X, et al. Among authors: kopan r. PLoS Genet. 2012;8(3):e1002577. doi: 10.1371/journal.pgen.1002577. Epub 2012 Mar 22. PLoS Genet. 2012. PMID: 22457635 Free PMC article.

7

Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch.

Ray WJ, Yao M, Mumm J, Schroeter EH, Saftig P, Wolfe M, Selkoe DJ, Kopan R, Goate AM. Ray WJ, et al. Among authors: kopan r. J Biol Chem. 1999 Dec 17;274(51):36801-7. doi: 10.1074/jbc.274.51.36801. J Biol Chem. 1999. PMID: 10593990 Free article.

8

Ectodomain shedding and intramembrane cleavage of mammalian Notch proteins is not regulated through oligomerization.

Vooijs M, Schroeter EH, Pan Y, Blandford M, Kopan R. Vooijs M, et al. Among authors: kopan r. J Biol Chem. 2004 Dec 3;279(49):50864-73. doi: 10.1074/jbc.M409430200. Epub 2004 Sep 23. J Biol Chem. 2004. PMID: 15448134 Free article.

9

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

Saxena MT, Schroeter EH, Mumm JS, Kopan R. Saxena MT, et al. Among authors: kopan r. J Biol Chem. 2001 Oct 26;276(43):40268-73. doi: 10.1074/jbc.M107234200. Epub 2001 Aug 22. J Biol Chem. 2001. PMID: 11518718 Free article.

10

Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

van Tetering G, van Diest P, Verlaan I, van der Wall E, Kopan R, Vooijs M. van Tetering G, et al. Among authors: kopan r. J Biol Chem. 2009 Nov 6;284(45):31018-27. doi: 10.1074/jbc.M109.006775. Epub 2009 Sep 2. J Biol Chem. 2009. PMID: 19726682 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

170 results

Search Page

Filters