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Page 1
New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part 2: [g]-fused and hetero-fused systems.
Micheli F, Bonanomi G, Braggio S, Capelli AM, Damiani F, Di Fabio R, Donati D, Gentile G, Hamprecht D, Perini O, Petrone M, Tedesco G, Terreni S, Worby A, Heidbreder C. Micheli F, et al. Among authors: petrone m. Bioorg Med Chem Lett. 2008 Feb 1;18(3):908-12. doi: 10.1016/j.bmcl.2007.12.042. Epub 2008 Jan 4. Bioorg Med Chem Lett. 2008. PMID: 18178090
1,2,4-triazol-3-yl-thiopropyl-tetrahydrobenzazepines: a series of potent and selective dopamine D(3) receptor antagonists.
Micheli F, Bonanomi G, Blaney FE, Braggio S, Capelli AM, Checchia A, Curcuruto O, Damiani F, Fabio RD, Donati D, Gentile G, Gribble A, Hamprecht D, Tedesco G, Terreni S, Tarsi L, Lightfoot A, Stemp G, Macdonald G, Smith A, Pecoraro M, Petrone M, Perini O, Piner J, Rossi T, Worby A, Pilla M, Valerio E, Griffante C, Mugnaini M, Wood M, Scott C, Andreoli M, Lacroix L, Schwarz A, Gozzi A, Bifone A, Ashby CR Jr, Hagan JJ, Heidbreder C. Micheli F, et al. Among authors: petrone m. J Med Chem. 2007 Oct 18;50(21):5076-89. doi: 10.1021/jm0705612. Epub 2007 Sep 15. J Med Chem. 2007. PMID: 17867665
New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part one: [h]-fused tricyclic systems.
Micheli F, Bonanomi G, Braggio S, Capelli AM, Celestini P, Damiani F, Di Fabio R, Donati D, Gagliardi S, Gentile G, Hamprecht D, Petrone M, Radaelli S, Tedesco G, Terreni S, Worby A, Heidbreder C. Micheli F, et al. Among authors: petrone m. Bioorg Med Chem Lett. 2008 Feb 1;18(3):901-7. doi: 10.1016/j.bmcl.2007.12.066. Epub 2008 Jan 3. Bioorg Med Chem Lett. 2008. PMID: 18248991
Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: synthesis and biological evaluation.
Micheli F, Pasquarello A, Tedesco G, Hamprecht D, Bonanomi G, Checchia A, Jaxa-Chamiec A, Damiani F, Davalli S, Donati D, Gallotti C, Petrone M, Rinaldi M, Riley G, Terreni S, Wood M. Micheli F, et al. Among authors: petrone m. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3906-12. doi: 10.1016/j.bmcl.2006.05.034. Epub 2006 May 30. Bioorg Med Chem Lett. 2006. PMID: 16730983
Evaluation of the role of intestinal and liver metabolism in the conversion of two different ester prodrugs of sanfetrinem to the parent drug in vitro and in vivo using different rat tissues and a surgically prepared rat model.
Braggio S, Ferrara A, Sartori M, Bottacini M, Zanelli U, Zonzini L, Petrone M. Braggio S, et al. Among authors: petrone m. Eur J Pharm Sci. 2002 Jul;16(1-2):45-51. doi: 10.1016/s0928-0987(02)00056-8. Eur J Pharm Sci. 2002. PMID: 12113890
Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.
Comley RA, Salinas CA, Slifstein M, Petrone M, Marzano C, Bennacef I, Shotbolt P, Van der Aart J, Neve M, Iavarone L, Gomeni R, Laruelle M, Gray FA, Gunn RN, Rabiner EA. Comley RA, et al. Among authors: petrone m. J Pharmacol Exp Ther. 2013 Aug;346(2):311-7. doi: 10.1124/jpet.112.202895. Epub 2013 May 17. J Pharmacol Exp Ther. 2013. PMID: 23685546 Clinical Trial.
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.
Schofield DJ, Irving L, Calo L, Bogstedt A, Rees G, Nuccitelli A, Narwal R, Petrone M, Roberts J, Brown L, Cusdin F, Dosanjh B, Lloyd C, Dobson C, Gurrell I, Fraser G, McFarlane M, Rockenstein E, Spencer B, Masliah E, Spillantini MG, Tan K, Billinton A, Vaughan T, Chessell I, Perkinton MS. Schofield DJ, et al. Among authors: petrone m. Neurobiol Dis. 2019 Dec;132:104582. doi: 10.1016/j.nbd.2019.104582. Epub 2019 Aug 21. Neurobiol Dis. 2019. PMID: 31445162 Free article.
410 results