Arteaga CL - Search Results

1

Inhibition of Hsp90 down-regulates mutant epidermal growth factor receptor (EGFR) expression and sensitizes EGFR mutant tumors to paclitaxel.

Sawai A, Chandarlapaty S, Greulich H, Gonen M, Ye Q, Arteaga CL, Sellers W, Rosen N, Solit DB. Sawai A, et al. Among authors: arteaga cl. Cancer Res. 2008 Jan 15;68(2):589-96. doi: 10.1158/0008-5472.CAN-07-1570. Cancer Res. 2008. PMID: 18199556 Free PMC article.

2

Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo.

Moulder SL, Yakes FM, Muthuswamy SK, Bianco R, Simpson JF, Arteaga CL. Moulder SL, et al. Among authors: arteaga cl. Cancer Res. 2001 Dec 15;61(24):8887-95. Cancer Res. 2001. PMID: 11751413

3

Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors.

Bianco R, Shin I, Ritter CA, Yakes FM, Basso A, Rosen N, Tsurutani J, Dennis PA, Mills GB, Arteaga CL. Bianco R, et al. Among authors: arteaga cl. Oncogene. 2003 May 8;22(18):2812-22. doi: 10.1038/sj.onc.1206388. Oncogene. 2003. PMID: 12743604

4

HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors.

Wang SE, Narasanna A, Perez-Torres M, Xiang B, Wu FY, Yang S, Carpenter G, Gazdar AF, Muthuswamy SK, Arteaga CL. Wang SE, et al. Among authors: arteaga cl. Cancer Cell. 2006 Jul;10(1):25-38. doi: 10.1016/j.ccr.2006.05.023. Cancer Cell. 2006. PMID: 16843263 Free article.

5

Association with HSP90 inhibits Cbl-mediated down-regulation of mutant epidermal growth factor receptors.

Yang S, Qu S, Perez-Tores M, Sawai A, Rosen N, Solit DB, Arteaga CL. Yang S, et al. Among authors: arteaga cl. Cancer Res. 2006 Jul 15;66(14):6990-7. doi: 10.1158/0008-5472.CAN-06-1042. Cancer Res. 2006. PMID: 16849543

6

Epidermal growth factor receptor (EGFR) antibody down-regulates mutant receptors and inhibits tumors expressing EGFR mutations.

Perez-Torres M, Guix M, Gonzalez A, Arteaga CL. Perez-Torres M, et al. Among authors: arteaga cl. J Biol Chem. 2006 Dec 29;281(52):40183-92. doi: 10.1074/jbc.M607958200. Epub 2006 Nov 1. J Biol Chem. 2006. PMID: 17082181 Free article.

7

Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells.

Bonine-Summers AR, Aakre ME, Brown KA, Arteaga CL, Pietenpol JA, Moses HL, Cheng N. Bonine-Summers AR, et al. Among authors: arteaga cl. Cancer Biol Ther. 2007 Apr;6(4):561-70. doi: 10.4161/cbt.6.4.3851. Cancer Biol Ther. 2007. PMID: 17495520 Free PMC article.

8

Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer.

Yang L, Amann JM, Kikuchi T, Porta R, Guix M, Gonzalez A, Park KH, Billheimer D, Arteaga CL, Tai HH, DuBois R, Carbone DP, Johnson DH. Yang L, et al. Among authors: arteaga cl. Cancer Res. 2007 Jun 15;67(12):5587-93. doi: 10.1158/0008-5472.CAN-06-2287. Cancer Res. 2007. PMID: 17575121

9

Human breast cancer cells selected for resistance to trastuzumab in vivo overexpress epidermal growth factor receptor and ErbB ligands and remain dependent on the ErbB receptor network.

Ritter CA, Perez-Torres M, Rinehart C, Guix M, Dugger T, Engelman JA, Arteaga CL. Ritter CA, et al. Among authors: arteaga cl. Clin Cancer Res. 2007 Aug 15;13(16):4909-19. doi: 10.1158/1078-0432.CCR-07-0701. Clin Cancer Res. 2007. PMID: 17699871

10

Knockdown of the transforming growth factor-beta type III receptor impairs motility and invasion of metastatic cancer cells.

Criswell TL, Dumont N, Barnett JV, Arteaga CL. Criswell TL, et al. Among authors: arteaga cl. Cancer Res. 2008 Sep 15;68(18):7304-12. doi: 10.1158/0008-5472.CAN-07-6777. Cancer Res. 2008. PMID: 18794117

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