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Page 1
Cdc7 kinase inhibitors: pyrrolopyridinones as potential antitumor agents. 1. Synthesis and structure-activity relationships.
Vanotti E, Amici R, Bargiotti A, Berthelsen J, Bosotti R, Ciavolella A, Cirla A, Cristiani C, D'Alessio R, Forte B, Isacchi A, Martina K, Menichincheri M, Molinari A, Montagnoli A, Orsini P, Pillan A, Roletto F, Scolaro A, Tibolla M, Valsasina B, Varasi M, Volpi D, Santocanale C. Vanotti E, et al. Among authors: berthelsen j. J Med Chem. 2008 Feb 14;51(3):487-501. doi: 10.1021/jm700956r. Epub 2008 Jan 18. J Med Chem. 2008. PMID: 18201066
First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery.
Menichincheri M, Bargiotti A, Berthelsen J, Bertrand JA, Bossi R, Ciavolella A, Cirla A, Cristiani C, Croci V, D'Alessio R, Fasolini M, Fiorentini F, Forte B, Isacchi A, Martina K, Molinari A, Montagnoli A, Orsini P, Orzi F, Pesenti E, Pezzetta D, Pillan A, Poggesi I, Roletto F, Scolaro A, Tatò M, Tibolla M, Valsasina B, Varasi M, Volpi D, Santocanale C, Vanotti E. Menichincheri M, et al. Among authors: berthelsen j. J Med Chem. 2009 Jan 22;52(2):293-307. doi: 10.1021/jm800977q. J Med Chem. 2009. PMID: 19115845
Drf1, a novel regulatory subunit for human Cdc7 kinase.
Montagnoli A, Bosotti R, Villa F, Rialland M, Brotherton D, Mercurio C, Berthelsen J, Santocanale C. Montagnoli A, et al. Among authors: berthelsen j. EMBO J. 2002 Jun 17;21(12):3171-81. doi: 10.1093/emboj/cdf290. EMBO J. 2002. PMID: 12065429 Free PMC article.
Prep1, a novel functional partner of Pbx proteins.
Berthelsen J, Zappavigna V, Mavilio F, Blasi F. Berthelsen J, et al. EMBO J. 1998 Mar 2;17(5):1423-33. doi: 10.1093/emboj/17.5.1423. EMBO J. 1998. PMID: 9482739 Free PMC article.
The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse.
Ferretti E, Schulz H, Talarico D, Blasi F, Berthelsen J. Ferretti E, et al. Among authors: berthelsen j. Mech Dev. 1999 May;83(1-2):53-64. doi: 10.1016/s0925-4773(99)00031-3. Mech Dev. 1999. PMID: 10381567 Free article.
EMBO J. 17, 1434-1445; Berthelsen, J., Zappavigna, V., Mavilio, F., Blasi, F., 1998c. Prep1, a novel functional partner of Pbx proteins. EMBO J. 17, 1423-1433). Here we demonstrate the presence of DNA-binding PREP1-PBX complexes also in murine cells. . …
EMBO J. 17, 1434-1445; Berthelsen, J., Zappavigna, V., Mavilio, F., Blasi, F., 1998c. Prep1, a novel functional partner …
86 results