Dean WL - Search Results

1

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

Clem B, Telang S, Clem A, Yalcin A, Meier J, Simmons A, Rasku MA, Arumugam S, Dean WL, Eaton J, Lane A, Trent JO, Chesney J. Clem B, et al. Among authors: dean wl. Mol Cancer Ther. 2008 Jan;7(1):110-20. doi: 10.1158/1535-7163.MCT-07-0482. Mol Cancer Ther. 2008. PMID: 18202014

2

Polymorphism and resolution of oncogene promoter quadruplex-forming sequences.

Miller MC, Le HT, Dean WL, Holt PA, Chaires JB, Trent JO. Miller MC, et al. Among authors: dean wl. Org Biomol Chem. 2011 Oct 26;9(22):7633-7. doi: 10.1039/c1ob05891f. Epub 2011 Sep 21. Org Biomol Chem. 2011. PMID: 21938285 Free PMC article.

3

Calculation of hydrodynamic properties for G-quadruplex nucleic acid structures from in silico bead models.

Le HT, Buscaglia R, Dean WL, Chaires JB, Trent JO. Le HT, et al. Among authors: dean wl. Top Curr Chem. 2013;330:179-210. doi: 10.1007/128_2012_351. Top Curr Chem. 2013. PMID: 22886555 Free PMC article.

4

Polyethylene glycol binding alters human telomere G-quadruplex structure by conformational selection.

Buscaglia R, Miller MC, Dean WL, Gray RD, Lane AN, Trent JO, Chaires JB. Buscaglia R, et al. Among authors: dean wl. Nucleic Acids Res. 2013 Sep;41(16):7934-46. doi: 10.1093/nar/gkt440. Epub 2013 Jun 26. Nucleic Acids Res. 2013. PMID: 23804761 Free PMC article.

5

Hydrodynamic Models of G-Quadruplex Structures.

Chaires JB, Dean WL, Le HT, Trent JO. Chaires JB, et al. Among authors: dean wl. Methods Enzymol. 2015;562:287-304. doi: 10.1016/bs.mie.2015.04.011. Epub 2015 Jun 19. Methods Enzymol. 2015. PMID: 26412657 Free PMC article.

6

Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.

Khan N, Shah PP, Ban D, Trigo-Mouriño P, Carneiro MG, DeLeeuw L, Dean WL, Trent JO, Beverly LJ, Konrad M, Lee D, Sabo TM. Khan N, et al. Among authors: dean wl. J Biol Chem. 2019 Aug 2;294(31):11920-11933. doi: 10.1074/jbc.RA119.009251. Epub 2019 Jun 14. J Biol Chem. 2019. PMID: 31201273 Free PMC article.

7

An improved model for the hTERT promoter quadruplex.

Chaires JB, Trent JO, Gray RD, Dean WL, Buscaglia R, Thomas SD, Miller DM. Chaires JB, et al. Among authors: dean wl. PLoS One. 2014 Dec 19;9(12):e115580. doi: 10.1371/journal.pone.0115580. eCollection 2014. PLoS One. 2014. PMID: 25526084 Free PMC article.

8

The solution structures of higher-order human telomere G-quadruplex multimers.

Monsen RC, Chakravarthy S, Dean WL, Chaires JB, Trent JO. Monsen RC, et al. Among authors: dean wl. Nucleic Acids Res. 2021 Feb 22;49(3):1749-1768. doi: 10.1093/nar/gkaa1285. Nucleic Acids Res. 2021. PMID: 33469644 Free PMC article.

9

Human POT1 unfolds G-quadruplexes by conformational selection.

Chaires JB, Gray RD, Dean WL, Monsen R, DeLeeuw LW, Stribinskis V, Trent JO. Chaires JB, et al. Among authors: dean wl. Nucleic Acids Res. 2020 May 21;48(9):4976-4991. doi: 10.1093/nar/gkaa202. Nucleic Acids Res. 2020. PMID: 32232414 Free PMC article.

10

An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation.

Le HT, Dean WL, Buscaglia R, Chaires JB, Trent JO. Le HT, et al. Among authors: dean wl. J Phys Chem B. 2014 May 22;118(20):5390-405. doi: 10.1021/jp502213y. Epub 2014 May 8. J Phys Chem B. 2014. PMID: 24779348 Free PMC article.

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