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Iodine‑131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma.
Brito AF, Abrantes AM, Teixo R, Pires AS, Ribeiro AC, Ferreira RF, Mascarenhas A, Puga T, Laranjo M, Caramelo F, Boin I, Jefferson DM, Gonçalves C, Martins R, Tavares I, Ribeiro IP, Sarmento-Ribeiro AB, Carreira IM, Souza D, Tralhão JG, Botelho MF. Brito AF, et al. Among authors: jefferson dm. Int J Oncol. 2020 Mar;56(3):709-727. doi: 10.3892/ijo.2020.4957. Epub 2020 Jan 10. Int J Oncol. 2020. PMID: 31922240 Free PMC article.
The biliary epithelium presents antigens to and activates natural killer T cells.
Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E. Schrumpf E, et al. Among authors: jefferson dm. Hepatology. 2015 Oct;62(4):1249-59. doi: 10.1002/hep.27840. Epub 2015 May 20. Hepatology. 2015. PMID: 25855031 Free PMC article.
Increased T-helper 2 cytokines in bile from patients with IgG4-related cholangitis disrupt the tight junction-associated biliary epithelial cell barrier.
Müller T, Beutler C, Picó AH, Otten M, Dürr A, Al-Abadi H, Guckelberger O, Meyer Zum Büschenfelde D, Jöhrens K, Volkmann M, Lankisch T, Voigtländer T, Anders M, Shibolet O, Jefferson DM, Podolsky DK, Fischer A, Veltzke-Schlieker W, Adler A, Baumgart DC, Sturm A, Wiedenmann B, Schott E, Berg T. Müller T, et al. Among authors: jefferson dm. Gastroenterology. 2013 May;144(5):1116-28. doi: 10.1053/j.gastro.2013.01.055. Epub 2013 Feb 4. Gastroenterology. 2013. PMID: 23391819
61 results