Graham RM - Search Results

1

Wide turn diversity in protein transmembrane helices implications for G-protein-coupled receptor and other polytopic membrane protein structure and function.

Riek RP, Finch AA, Begg GE, Graham RM. Riek RP, et al. Among authors: graham rm. Mol Pharmacol. 2008 Apr;73(4):1092-104. doi: 10.1124/mol.107.043042. Epub 2008 Jan 17. Mol Pharmacol. 2008. PMID: 18202304

2

Genomic organization and expression of the human alpha 1B-adrenergic receptor.

Ramarao CS, Denker JM, Perez DM, Gaivin RJ, Riek RP, Graham RM. Ramarao CS, et al. Among authors: graham rm. J Biol Chem. 1992 Oct 25;267(30):21936-45. J Biol Chem. 1992. PMID: 1328250 Free article.

3

Identification and structural characterization of alpha 1-adrenergic receptor subtypes.

Terman BI, Riek RP, Grodski A, Hess HJ, Graham RM. Terman BI, et al. Among authors: graham rm. Mol Pharmacol. 1990 Apr;37(4):526-34. Mol Pharmacol. 1990. PMID: 2157960

4

A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. II. Purification, characterization, and reconstitution.

Im MJ, Riek RP, Graham RM. Im MJ, et al. Among authors: graham rm. J Biol Chem. 1990 Nov 5;265(31):18952-60. J Biol Chem. 1990. PMID: 2172240 Free article.

5

Evolutionary conservation of both the hydrophilic and hydrophobic nature of transmembrane residues.

Riek RP, Handschumacher MD, Sung SS, Tan M, Glynias MJ, Schluchter MD, Novotny J, Graham RM. Riek RP, et al. Among authors: graham rm. J Theor Biol. 1995 Feb 7;172(3):245-58. doi: 10.1006/jtbi.1995.0021. J Theor Biol. 1995. PMID: 7715195

6

Functional characterization of ribozymes expressed using U1 and T7 vectors for the intracellular cleavage of ANF mRNA.

De Young MB, Kincade-Denker J, Boehm CA, Riek RP, Mamone JA, McSwiggen JA, Graham RM. De Young MB, et al. Among authors: graham rm. Biochemistry. 1994 Oct 11;33(40):12127-38. doi: 10.1021/bi00206a016. Biochemistry. 1994. PMID: 7918434

7

Non-alpha-helical elements modulate polytopic membrane protein architecture.

Riek RP, Rigoutsos I, Novotny J, Graham RM. Riek RP, et al. Among authors: graham rm. J Mol Biol. 2001 Feb 16;306(2):349-62. doi: 10.1006/jmbi.2000.4402. J Mol Biol. 2001. PMID: 11237604

8

Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity.

Murthy SN, Iismaa S, Begg G, Freymann DM, Graham RM, Lorand L. Murthy SN, et al. Among authors: graham rm. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2738-42. doi: 10.1073/pnas.052715799. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867764 Free PMC article.

9

Mutation of a single TMVI residue, Phe(282), in the beta(2)-adrenergic receptor results in structurally distinct activated receptor conformations.

Chen S, Lin F, Xu M, Riek RP, Novotny J, Graham RM. Chen S, et al. Among authors: graham rm. Biochemistry. 2002 May 14;41(19):6045-53. doi: 10.1021/bi012189c. Biochemistry. 2002. PMID: 11993999

10

Synthesis and biological evaluation of bicyclic and tricyclic substituted nortropane derivatives: discovery of a novel selective alpha1D-adrenergic receptor ligand.

McGinty SJ, Finch A, Griffith R, Graham RM, Bremner JB. McGinty SJ, et al. Among authors: graham rm. Bioorg Med Chem. 2004 Nov 1;12(21):5639-50. doi: 10.1016/j.bmc.2004.07.063. Bioorg Med Chem. 2004. PMID: 15465342

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