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Two N-terminal domains of Kv4 K(+) channels regulate binding to and modulation by KChIP1.
Scannevin RH, Wang K, Jow F, Megules J, Kopsco DC, Edris W, Carroll KC, Lü Q, Xu W, Xu Z, Katz AH, Olland S, Lin L, Taylor M, Stahl M, Malakian K, Somers W, Mosyak L, Bowlby MR, Chanda P, Rhodes KJ. Scannevin RH, et al. Among authors: bowlby mr. Neuron. 2004 Feb 19;41(4):587-98. doi: 10.1016/s0896-6273(04)00049-2. Neuron. 2004. PMID: 14980207 Free article.
Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the 5-hydroxytryptamine(2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b']di pyrrole-1(2H)-carboxamide).
Dunlop J, Lock T, Jow B, Sitzia F, Grauer S, Jow F, Kramer A, Bowlby MR, Randall A, Kowal D, Gilbert A, Comery TA, Larocque J, Soloveva V, Brown J, Roncarati R. Dunlop J, et al. Among authors: bowlby mr. J Pharmacol Exp Ther. 2009 Mar;328(3):766-76. doi: 10.1124/jpet.108.146514. Epub 2008 Dec 2. J Pharmacol Exp Ther. 2009. PMID: 19050173
Amiloride is neuroprotective in an MPTP model of Parkinson's disease.
Arias RL, Sung ML, Vasylyev D, Zhang MY, Albinson K, Kubek K, Kagan N, Beyer C, Lin Q, Dwyer JM, Zaleska MM, Bowlby MR, Dunlop J, Monaghan M. Arias RL, et al. Among authors: bowlby mr. Neurobiol Dis. 2008 Sep;31(3):334-41. doi: 10.1016/j.nbd.2008.05.008. Epub 2008 Jul 7. Neurobiol Dis. 2008. PMID: 18606547
Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities.
Ruan B, Pong K, Jow F, Bowlby M, Crozier RA, Liu D, Liang S, Chen Y, Mercado ML, Feng X, Bennett F, von Schack D, McDonald L, Zaleska MM, Wood A, Reinhart PH, Magolda RL, Skotnicki J, Pangalos MN, Koehn FE, Carter GT, Abou-Gharbia M, Graziani EI. Ruan B, et al. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):33-8. doi: 10.1073/pnas.0710424105. Epub 2007 Dec 27. Proc Natl Acad Sci U S A. 2008. PMID: 18162540 Free PMC article.
47 results