Mengwasser KE - Search Results

1

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP.

Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ. Yun CH, et al. Among authors: mengwasser ke. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2070-5. doi: 10.1073/pnas.0709662105. Epub 2008 Jan 28. Proc Natl Acad Sci U S A. 2008. PMID: 18227510 Free PMC article.

2

Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.

Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ. Davoli T, et al. Among authors: mengwasser ke. Genes Dev. 2016 Dec 15;30(24):2684-2695. doi: 10.1101/gad.290122.116. Genes Dev. 2016. PMID: 28087713 Free PMC article.

3

Genetic analysis of cancer drivers reveals cohesin and CTCF as suppressors of PD-L1.

Oreskovic E, Wheeler EC, Mengwasser KE, Fujimura E, Martin TD, Tothova Z, Elledge SJ. Oreskovic E, et al. Among authors: mengwasser ke. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2120540119. doi: 10.1073/pnas.2120540119. Proc Natl Acad Sci U S A. 2022. PMID: 35149558 Free PMC article.

4

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

Mengwasser KE, Adeyemi RO, Leng Y, Choi MY, Clairmont C, D'Andrea AD, Elledge SJ. Mengwasser KE, et al. Mol Cell. 2019 Mar 7;73(5):885-899.e6. doi: 10.1016/j.molcel.2018.12.008. Epub 2019 Jan 24. Mol Cell. 2019. PMID: 30686591 Free PMC article.

5

Cumulative haploinsufficiency and triplosensitivity drive aneuploidy patterns and shape the cancer genome.

Davoli T, Xu AW, Mengwasser KE, Sack LM, Yoon JC, Park PJ, Elledge SJ. Davoli T, et al. Among authors: mengwasser ke. Cell. 2013 Nov 7;155(4):948-62. doi: 10.1016/j.cell.2013.10.011. Epub 2013 Oct 31. Cell. 2013. PMID: 24183448 Free PMC article.

6

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

Elman JS, Ni TK, Mengwasser KE, Jin D, Wronski A, Elledge SJ, Kuperwasser C. Elman JS, et al. Among authors: mengwasser ke. Cell Rep. 2019 Sep 24;28(13):3435-3449.e5. doi: 10.1016/j.celrep.2019.08.060. Cell Rep. 2019. PMID: 31553912 Free PMC article.

7

Hirudin binding reveals key determinants of thrombin allostery.

Mengwasser KE, Bush LA, Shih P, Cantwell AM, Di Cera E. Mengwasser KE, et al. J Biol Chem. 2005 Jul 22;280(29):26997-7003. doi: 10.1074/jbc.M502678200. Epub 2005 May 27. J Biol Chem. 2005. PMID: 15923186 Free article.

8

LPS ligand and culture additives improve production of monomeric MD-1 and 2 in Pichia pastoris by decreasing aggregation and intermolecular disulfide bonding.

Mengwasser KE, Bryant CE, Gay NJ, Gangloff M. Mengwasser KE, et al. Protein Expr Purif. 2011 Apr;76(2):173-83. doi: 10.1016/j.pep.2010.11.018. Epub 2010 Dec 2. Protein Expr Purif. 2011. PMID: 21130168 Free PMC article.

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