Unger A - Search Results

1

In vitro metabolism of 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] acetic acid (licofelone, ML3000), an inhibitor of cyclooxygenase-1 and -2 and 5-lipoxygenase.

Albrecht W, Unger A, Nussler AK, Laufer S. Albrecht W, et al. Among authors: unger a. Drug Metab Dispos. 2008 May;36(5):894-903. doi: 10.1124/dmd.108.020347. Epub 2008 Feb 11. Drug Metab Dispos. 2008. PMID: 18268076

2

2-Acylaminopyridin-4-ylimidazoles as p38 MAP kinase inhibitors: Design, synthesis, and biological and metabolic evaluations.

Ziegler K, Hauser DR, Unger A, Albrecht W, Laufer SA. Ziegler K, et al. Among authors: unger a. ChemMedChem. 2009 Nov;4(11):1939-48. doi: 10.1002/cmdc.200900242. ChemMedChem. 2009. PMID: 19731280

3

Discovery of N-{4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-acetamide (CBS-3595), a Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα-Related Diseases.

Albrecht W, Unger A, Bauer SM, Laufer SA. Albrecht W, et al. Among authors: unger a. J Med Chem. 2017 Jul 13;60(13):5290-5305. doi: 10.1021/acs.jmedchem.6b01647. Epub 2017 Jun 27. J Med Chem. 2017. PMID: 28613871

4

Impact of p38 MAP Kinase Inhibitors on LPS-Induced Release of TNF-α in Whole Blood and Primary Cells from Different Species.

Fehr S, Unger A, Schaeffeler E, Herrmann S, Laufer S, Schwab M, Albrecht W. Fehr S, et al. Among authors: unger a. Cell Physiol Biochem. 2015;36(6):2237-49. doi: 10.1159/000430188. Epub 2015 Jul 24. Cell Physiol Biochem. 2015. PMID: 26279429 Free article.

5

Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor.

Engel J, Smith S, Lategahn J, Tumbrink HL, Goebel L, Becker C, Hennes E, Keul M, Unger A, Müller H, Baumann M, Schultz-Fademrecht C, Günther G, Hengstler JG, Rauh D. Engel J, et al. Among authors: unger a. J Med Chem. 2017 Sep 28;60(18):7725-7744. doi: 10.1021/acs.jmedchem.7b00515. Epub 2017 Sep 18. J Med Chem. 2017. PMID: 28853575

6

Targeting gain of function and resistance mutations in Abl and KIT by hybrid compound design.

Richters A, Ketzer J, Getlik M, Grütter C, Schneider R, Heuckmann JM, Heynck S, Sos ML, Gupta A, Unger A, Schultz-Fademrecht C, Thomas RK, Bauer S, Rauh D. Richters A, et al. Among authors: unger a. J Med Chem. 2013 Jul 25;56(14):5757-72. doi: 10.1021/jm4004076. Epub 2013 Jul 10. J Med Chem. 2013. PMID: 23773153

7

Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.

Lategahn J, Hardick J, Grabe T, Niggenaber J, Jeyakumar K, Keul M, Tumbrink HL, Becker C, Hodson L, Kirschner T, Klövekorn P, Ketzer J, Baumann M, Terheyden S, Unger A, Weisner J, Müller MP, van Otterlo WAL, Bauer S, Rauh D. Lategahn J, et al. Among authors: unger a. J Med Chem. 2020 Oct 22;63(20):11725-11755. doi: 10.1021/acs.jmedchem.0c00870. Epub 2020 Sep 30. J Med Chem. 2020. PMID: 32931277

8

Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt.

Meijer FA, Saris AOWM, Doveston RG, Oerlemans GJM, de Vries RMJM, Somsen BA, Unger A, Klebl B, Ottmann C, Cossar PJ, Brunsveld L. Meijer FA, et al. Among authors: unger a. J Med Chem. 2021 Jul 8;64(13):9238-9258. doi: 10.1021/acs.jmedchem.1c00475. Epub 2021 May 19. J Med Chem. 2021. PMID: 34008974 Free PMC article.

9

Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain.

Falk S, Appel CK, Bennedbæk HB, Al-Dihaissy T, Unger A, Dinkel K, Heegaard AM. Falk S, et al. Among authors: unger a. Eur J Pharmacol. 2019 Feb 15;845:48-55. doi: 10.1016/j.ejphar.2018.12.032. Epub 2018 Dec 22. Eur J Pharmacol. 2019. PMID: 30582910

10

A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.

Hutterer C, Eickhoff J, Milbradt J, Korn K, Zeitträger I, Bahsi H, Wagner S, Zischinsky G, Wolf A, Degenhart C, Unger A, Baumann M, Klebl B, Marschall M. Hutterer C, et al. Among authors: unger a. Antimicrob Agents Chemother. 2015 Apr;59(4):2062-71. doi: 10.1128/AAC.04534-14. Epub 2015 Jan 26. Antimicrob Agents Chemother. 2015. PMID: 25624324 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

361 results

Search Page

Filters