Lord P - Search Results

1

Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat.

Fielden MR, Nie A, McMillian M, Elangbam CS, Trela BA, Yang Y, Dunn RT 2nd, Dragan Y, Fransson-Stehen R, Bogdanffy M, Adams SP, Foster WR, Chen SJ, Rossi P, Kasper P, Jacobson-Kram D, Tatsuoka KS, Wier PJ, Gollub J, Halbert DN, Roter A, Young JK, Sina JF, Marlowe J, Martus HJ, Aubrecht J, Olaharski AJ, Roome N, Nioi P, Pardo I, Snyder R, Perry R, Lord P, Mattes W, Car BD; Predictive Safety Testing Consortium; Carcinogenicity Working Group. Fielden MR, et al. Among authors: lord p. Toxicol Sci. 2008 May;103(1):28-34. doi: 10.1093/toxsci/kfn022. Epub 2008 Feb 14. Toxicol Sci. 2008. PMID: 18281259

2

Application of genomics in preclinical drug safety evaluation.

Lord PG, Nie A, McMillian M. Lord PG, et al. Basic Clin Pharmacol Toxicol. 2006 Jun;98(6):537-46. doi: 10.1111/j.1742-7843.2006.pto_444.x. Basic Clin Pharmacol Toxicol. 2006. PMID: 16700814 Free article. Review.

3

Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity.

Nie AY, McMillian M, Parker JB, Leone A, Bryant S, Yieh L, Bittner A, Nelson J, Carmen A, Wan J, Lord PG. Nie AY, et al. Mol Carcinog. 2006 Dec;45(12):914-33. doi: 10.1002/mc.20205. Mol Carcinog. 2006. PMID: 16921489

4

The evolution of gene expression studies in drug safety assessment.

Lord PG, Nie A, McMillian M. Lord PG, et al. Toxicol Mech Methods. 2006;16(2-3):51-8. doi: 10.1080/15376520600558200. Toxicol Mech Methods. 2006. PMID: 20020997

5

Oxidative stress/reactive metabolite gene expression signature in rat liver detects idiosyncratic hepatotoxicants.

Leone A, Nie A, Brandon Parker J, Sawant S, Piechta LA, Kelley MF, Mark Kao L, Jim Proctor S, Verheyen G, Johnson MD, Lord PG, McMillian MK. Leone A, et al. Toxicol Appl Pharmacol. 2014 Mar 15;275(3):189-97. doi: 10.1016/j.taap.2014.01.017. Epub 2014 Jan 29. Toxicol Appl Pharmacol. 2014. PMID: 24486436

6

Drug-induced oxidative stress in rat liver from a toxicogenomics perspective.

McMillian M, Nie A, Parker JB, Leone A, Kemmerer M, Bryant S, Herlich J, Yieh L, Bittner A, Liu X, Wan J, Johnson MD, Lord P. McMillian M, et al. Among authors: lord p. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):171-8. doi: 10.1016/j.taap.2005.02.031. Toxicol Appl Pharmacol. 2005. PMID: 15982685 Review.

7

Evaluation of felbamate and other antiepileptic drug toxicity potential based on hepatic protein covalent binding and gene expression.

Leone AM, Kao LM, McMillian MK, Nie AY, Parker JB, Kelley MF, Usuki E, Parkinson A, Lord PG, Johnson MD. Leone AM, et al. Chem Res Toxicol. 2007 Apr;20(4):600-8. doi: 10.1021/tx600351g. Epub 2007 Mar 24. Chem Res Toxicol. 2007. PMID: 17381134

8

Hepatic expression of heme oxygenase-1 and antioxidant response element-mediated genes following administration of ethinyl estradiol to rats.

Morio LA, Leone A, Sawant SP, Nie AY, Parker JB, Taggart P, Barron AM, McMillian MK, Lord P. Morio LA, et al. Among authors: lord p. Toxicol Appl Pharmacol. 2006 Nov 1;216(3):416-25. doi: 10.1016/j.taap.2006.06.016. Epub 2006 Jul 14. Toxicol Appl Pharmacol. 2006. PMID: 16926038

9

Release of (and lessons learned from mining) a pioneering large toxicogenomics database.

Sandhu KS, Veeramachaneni V, Yao X, Nie A, Lord P, Amaratunga D, McMillian MK, Verheyen GR. Sandhu KS, et al. Among authors: lord p. Pharmacogenomics. 2015 Jul;16(8):779-801. doi: 10.2217/pgs.15.38. Epub 2015 Jun 12. Pharmacogenomics. 2015. PMID: 26067483

10

Toward a checklist for exchange and interpretation of data from a toxicology study.

Fostel JM, Burgoon L, Zwickl C, Lord P, Corton JC, Bushel PR, Cunningham M, Fan L, Edwards SW, Hester S, Stevens J, Tong W, Waters M, Yang C, Tennant R. Fostel JM, et al. Among authors: lord p. Toxicol Sci. 2007 Sep;99(1):26-34. doi: 10.1093/toxsci/kfm090. Epub 2007 Apr 17. Toxicol Sci. 2007. PMID: 17442663

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