Hong S - Search Results

1

LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model.

Nazer B, Hong S, Selkoe DJ. Nazer B, et al. Among authors: hong s. Neurobiol Dis. 2008 Apr;30(1):94-102. doi: 10.1016/j.nbd.2007.12.005. Epub 2008 Jan 5. Neurobiol Dis. 2008. PMID: 18289866 Free PMC article.

2

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake.

Li S, Hong S, Shepardson NE, Walsh DM, Shankar GM, Selkoe D. Li S, et al. Among authors: hong s. Neuron. 2009 Jun 25;62(6):788-801. doi: 10.1016/j.neuron.2009.05.012. Neuron. 2009. PMID: 19555648 Free PMC article.

3

Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation.

Hong S, Quintero-Monzon O, Ostaszewski BL, Podlisny DR, Cavanaugh WT, Yang T, Holtzman DM, Cirrito JR, Selkoe DJ. Hong S, et al. J Neurosci. 2011 Nov 2;31(44):15861-9. doi: 10.1523/JNEUROSCI.3272-11.2011. J Neurosci. 2011. PMID: 22049429 Free PMC article.

4

New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF.

Yang T, Hong S, O'Malley T, Sperling RA, Walsh DM, Selkoe DJ. Yang T, et al. Among authors: hong s. Alzheimers Dement. 2013 Mar;9(2):99-112. doi: 10.1016/j.jalz.2012.11.005. Epub 2013 Jan 30. Alzheimers Dement. 2013. PMID: 23375565 Free PMC article.

5

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes.

Hong S, Ostaszewski BL, Yang T, O'Malley TT, Jin M, Yanagisawa K, Li S, Bartels T, Selkoe DJ. Hong S, et al. Neuron. 2014 Apr 16;82(2):308-19. doi: 10.1016/j.neuron.2014.02.027. Epub 2014 Mar 27. Neuron. 2014. PMID: 24685176 Free PMC article.

6

Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.

Chen AC, Kim S, Shepardson N, Patel S, Hong S, Selkoe DJ. Chen AC, et al. Among authors: hong s. J Cell Biol. 2015 Dec 21;211(6):1157-76. doi: 10.1083/jcb.201502001. J Cell Biol. 2015. PMID: 26694839 Free PMC article.

7

Complement and microglia mediate early synapse loss in Alzheimer mouse models.

Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan S, Merry KM, Shi Q, Rosenthal A, Barres BA, Lemere CA, Selkoe DJ, Stevens B. Hong S, et al. Science. 2016 May 6;352(6286):712-716. doi: 10.1126/science.aad8373. Epub 2016 Mar 31. Science. 2016. PMID: 27033548 Free PMC article.

8

Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia.

Fu H, Liu B, Frost JL, Hong S, Jin M, Ostaszewski B, Shankar GM, Costantino IM, Carroll MC, Mayadas TN, Lemere CA. Fu H, et al. Among authors: hong s. Glia. 2012 May;60(6):993-1003. doi: 10.1002/glia.22331. Epub 2012 Mar 21. Glia. 2012. PMID: 22438044 Free PMC article.

9

New insights on the role of microglia in synaptic pruning in health and disease.

Hong S, Dissing-Olesen L, Stevens B. Hong S, et al. Curr Opin Neurobiol. 2016 Feb;36:128-34. doi: 10.1016/j.conb.2015.12.004. Epub 2015 Dec 30. Curr Opin Neurobiol. 2016. PMID: 26745839 Free PMC article. Review.

10

Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.

Shi Q, Chowdhury S, Ma R, Le KX, Hong S, Caldarone BJ, Stevens B, Lemere CA. Shi Q, et al. Among authors: hong s. Sci Transl Med. 2017 May 31;9(392):eaaf6295. doi: 10.1126/scitranslmed.aaf6295. Sci Transl Med. 2017. PMID: 28566429 Free PMC article.

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