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Page 1
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1.
Petropoulos CJ, Parkin NT, Limoli KL, Lie YS, Wrin T, Huang W, Tian H, Smith D, Winslow GA, Capon DJ, Whitcomb JM. Petropoulos CJ, et al. Among authors: parkin nt. Antimicrob Agents Chemother. 2000 Apr;44(4):920-8. doi: 10.1128/AAC.44.4.920-928.2000. Antimicrob Agents Chemother. 2000. PMID: 10722492 Free PMC article.
Design and profiling of GS-9148, a novel nucleotide analog active against nucleoside-resistant variants of human immunodeficiency virus type 1, and its orally bioavailable phosphonoamidate prodrug, GS-9131.
Cihlar T, Ray AS, Boojamra CG, Zhang L, Hui H, Laflamme G, Vela JE, Grant D, Chen J, Myrick F, White KL, Gao Y, Lin KY, Douglas JL, Parkin NT, Carey A, Pakdaman R, Mackman RL. Cihlar T, et al. Antimicrob Agents Chemother. 2008 Feb;52(2):655-65. doi: 10.1128/AAC.01215-07. Epub 2007 Dec 3. Antimicrob Agents Chemother. 2008. PMID: 18056282 Free PMC article.
Identification and structural characterization of I84C and I84A mutations that are associated with high-level resistance to human immunodeficiency virus protease inhibitors and impair viral replication.
Mo H, Parkin N, Stewart KD, Lu L, Dekhtyar T, Kempf DJ, Molla A. Mo H, et al. Among authors: parkin n. Antimicrob Agents Chemother. 2007 Feb;51(2):732-5. doi: 10.1128/AAC.00690-06. Epub 2006 Nov 13. Antimicrob Agents Chemother. 2007. PMID: 17101675 Free PMC article.
Mutation D30N is not preferentially selected by human immunodeficiency virus type 1 subtype C in the development of resistance to nelfinavir.
Grossman Z, Paxinos EE, Averbuch D, Maayan S, Parkin NT, Engelhard D, Lorber M, Istomin V, Shaked Y, Mendelson E, Ram D, Petropoulos CJ, Schapiro JM. Grossman Z, et al. Antimicrob Agents Chemother. 2004 Jun;48(6):2159-65. doi: 10.1128/AAC.48.6.2159-2165.2004. Antimicrob Agents Chemother. 2004. PMID: 15155216 Free PMC article. Clinical Trial.
162 results