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Deficient mineralization of intramembranous bone in vitamin D-24-hydroxylase-ablated mice is due to elevated 1,25-dihydroxyvitamin D and not to the absence of 24,25-dihydroxyvitamin D.
St-Arnaud R, Arabian A, Travers R, Barletta F, Raval-Pandya M, Chapin K, Depovere J, Mathieu C, Christakos S, Demay MB, Glorieux FH. St-Arnaud R, et al. Among authors: arabian a. Endocrinology. 2000 Jul;141(7):2658-66. doi: 10.1210/endo.141.7.7579. Endocrinology. 2000. PMID: 10875271
1α,24(S)(OH)2D2 normalizes bone morphology and serum parathyroid hormone without hypercalcemia in 25-hydroxyvitamin D-1-hydroxylase (CYP27B1)-deficient mice, an animal model of vitamin D deficiency with secondary hyperparathyroidism.
St-Arnaud R, Arabian A, Yu VW, Akhouayri O, Knutson JC, Strugnell SA. St-Arnaud R, et al. Among authors: arabian a. J Endocrinol Invest. 2008 Aug;31(8):711-7. doi: 10.1007/BF03346420. J Endocrinol Invest. 2008. PMID: 18852532
44 results