Metcalfe CL - Search Results

1

Iron oxidation state modulates active site structure in a heme peroxidase.

Badyal SK, Metcalfe CL, Basran J, Efimov I, Moody PC, Raven EL. Badyal SK, et al. Among authors: metcalfe cl. Biochemistry. 2008 Apr 15;47(15):4403-9. doi: 10.1021/bi702337n. Epub 2008 Mar 20. Biochemistry. 2008. PMID: 18351739

2

Engineering the substrate specificity and reactivity of a heme protein: creation of an ascorbate binding site in cytochrome c peroxidase.

Murphy EJ, Metcalfe CL, Basran J, Moody PC, Raven EL. Murphy EJ, et al. Among authors: metcalfe cl. Biochemistry. 2008 Dec 30;47(52):13933-41. doi: 10.1021/bi801480r. Biochemistry. 2008. PMID: 19061385

3

Peroxide-dependent formation of a covalent link between Trp51 and the heme in cytochrome c peroxidase.

Pipirou Z, Guallar V, Basran J, Metcalfe CL, Murphy EJ, Bottrill AR, Mistry SC, Raven EL. Pipirou Z, et al. Among authors: metcalfe cl. Biochemistry. 2009 Apr 28;48(16):3593-9. doi: 10.1021/bi802210g. Biochemistry. 2009. PMID: 19249872

4

Evidence for heme oxygenase activity in a heme peroxidase.

Badyal SK, Eaton G, Mistry S, Pipirou Z, Basran J, Metcalfe CL, Gumiero A, Handa S, Moody PC, Raven EL. Badyal SK, et al. Among authors: metcalfe cl. Biochemistry. 2009 Jun 9;48(22):4738-46. doi: 10.1021/bi900118j. Biochemistry. 2009. PMID: 19309109

5

An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective.

Gumiero A, Murphy EJ, Metcalfe CL, Moody PC, Raven EL. Gumiero A, et al. Among authors: metcalfe cl. Arch Biochem Biophys. 2010 Aug 1;500(1):13-20. doi: 10.1016/j.abb.2010.02.015. Epub 2010 Mar 4. Arch Biochem Biophys. 2010. PMID: 20206594 Review.

6

Nature of the ferryl heme in compounds I and II.

Gumiero A, Metcalfe CL, Pearson AR, Raven EL, Moody PC. Gumiero A, et al. Among authors: metcalfe cl. J Biol Chem. 2011 Jan 14;286(2):1260-8. doi: 10.1074/jbc.M110.183483. Epub 2010 Nov 8. J Biol Chem. 2011. PMID: 21062738 Free PMC article.

7

Proton delivery to ferryl heme in a heme peroxidase: enzymatic use of the Grotthuss mechanism.

Efimov I, Badyal SK, Metcalfe CL, Macdonald I, Gumiero A, Raven EL, Moody PC. Efimov I, et al. Among authors: metcalfe cl. J Am Chem Soc. 2011 Oct 5;133(39):15376-83. doi: 10.1021/ja2007017. Epub 2011 Sep 14. J Am Chem Soc. 2011. PMID: 21819069

8

Crystal structure of guaiacol and phenol bound to a heme peroxidase.

Murphy EJ, Metcalfe CL, Nnamchi C, Moody PC, Raven EL. Murphy EJ, et al. Among authors: metcalfe cl. FEBS J. 2012 May;279(9):1632-9. doi: 10.1111/j.1742-4658.2011.08425.x. Epub 2011 Dec 5. FEBS J. 2012. PMID: 22093282 Free article.

9

Heme enzymes. Neutron cryo-crystallography captures the protonation state of ferryl heme in a peroxidase.

Casadei CM, Gumiero A, Metcalfe CL, Murphy EJ, Basran J, Concilio MG, Teixeira SC, Schrader TE, Fielding AJ, Ostermann A, Blakeley MP, Raven EL, Moody PC. Casadei CM, et al. Among authors: metcalfe cl. Science. 2014 Jul 11;345(6193):193-7. doi: 10.1126/science.1254398. Epub 2014 Jul 10. Science. 2014. PMID: 25013070

10

Autocatalytic formation of green heme: evidence for H2O2-dependent formation of a covalent methionine-heme linkage in ascorbate peroxidase.

Metcalfe CL, Ott M, Patel N, Singh K, Mistry SC, Goff HM, Raven EL. Metcalfe CL, et al. J Am Chem Soc. 2004 Dec 15;126(49):16242-8. doi: 10.1021/ja048242c. J Am Chem Soc. 2004. PMID: 15584761

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