Adjei AA - Search Results

1

Phase I pharmacokinetic and pharmacodynamic study of the oral, small-molecule mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) in patients with advanced cancers.

Adjei AA, Cohen RB, Franklin W, Morris C, Wilson D, Molina JR, Hanson LJ, Gore L, Chow L, Leong S, Maloney L, Gordon G, Simmons H, Marlow A, Litwiler K, Brown S, Poch G, Kane K, Haney J, Eckhardt SG. Adjei AA, et al. J Clin Oncol. 2008 May 1;26(13):2139-46. doi: 10.1200/JCO.2007.14.4956. Epub 2008 Apr 7. J Clin Oncol. 2008. PMID: 18390968 Free PMC article. Clinical Trial.

2

Pharmacokinetic, oral bioavailability, and safety study of fluorouracil in patients treated with 776C85, an inactivator of dihydropyrimidine dehydrogenase.

Baker SD, Khor SP, Adjei AA, Doucette M, Spector T, Donehower RC, Grochow LB, Sartorius SE, Noe DA, Hohneker JA, Rowinsky EK. Baker SD, et al. Among authors: adjei aa. J Clin Oncol. 1996 Dec;14(12):3085-96. doi: 10.1200/JCO.1996.14.12.3085. J Clin Oncol. 1996. PMID: 8955653 Clinical Trial.

3

Phase I and pharmacokinetic study of irinotecan and docetaxel in patients with advanced solid tumors: preliminary evidence of clinical activity.

Adjei AA, Klein CE, Kastrissios H, Goldberg RM, Alberts SR, Pitot HC, Sloan JA, Reid JM, Hanson LJ, Atherton P, Rubin J, Erlichman C. Adjei AA, et al. J Clin Oncol. 2000 Mar;18(5):1116-23. doi: 10.1200/JCO.2000.18.5.1116. J Clin Oncol. 2000. PMID: 10694565 Clinical Trial.

4

Phase I and pharmacologic study of sequences of gemcitabine and the multitargeted antifolate agent in patients with advanced solid tumors.

Adjei AA, Erlichman C, Sloan JA, Reid JM, Pitot HC, Goldberg RM, Peethambaram P, Atherton P, Hanson LJ, Alberts SR, Jett J. Adjei AA, et al. J Clin Oncol. 2000 Apr;18(8):1748-57. doi: 10.1200/JCO.2000.18.8.1748. J Clin Oncol. 2000. PMID: 10764436 Clinical Trial.

5

A Phase I trial of the farnesyl transferase inhibitor SCH66336: evidence for biological and clinical activity.

Adjei AA, Erlichman C, Davis JN, Cutler DL, Sloan JA, Marks RS, Hanson LJ, Svingen PA, Atherton P, Bishop WR, Kirschmeier P, Kaufmann SH. Adjei AA, et al. Cancer Res. 2000 Apr 1;60(7):1871-7. Cancer Res. 2000. PMID: 10766174 Clinical Trial.

6

Phase I study of the matrix metalloproteinase inhibitor, BAY 12-9566.

Erlichman C, Adjei AA, Alberts SR, Sloan JA, Goldberg RM, Pitot HC, Rubin J, Atherton PJ, Klee GG, Humphrey R. Erlichman C, et al. Among authors: adjei aa. Ann Oncol. 2001 Mar;12(3):389-95. doi: 10.1023/a:1011183905848. Ann Oncol. 2001. PMID: 11332153 Free article. Clinical Trial.

7

Comparative pharmacokinetic study of continuous venous infusion fluorouracil and oral fluorouracil with eniluracil in patients with advanced solid tumors.

Adjei AA, Reid JM, Diasio RB, Sloan JA, Smith DA, Rubin J, Pitot HC, Alberts SR, Goldberg RM, Hanson LJ, Atherton P, Ames MM, Erlichman C. Adjei AA, et al. J Clin Oncol. 2002 Mar 15;20(6):1683-91. doi: 10.1200/JCO.2002.20.6.1683. J Clin Oncol. 2002. PMID: 11896120 Clinical Trial.

8

A phase I and pharmacologic study of pyrazoloacridine (NSC 366140) and carboplatin in patients with advanced cancer.

Adjei AA, Reid JM, Erlichman C, Sloan JA, Pitot HC, Alberts SR, Goldberg RM, Hanson LJ, Ruben S, Boemer SA, Atherton P, Ames MM, Kaufmann SH. Adjei AA, et al. Invest New Drugs. 2002 Aug;20(3):297-304. doi: 10.1023/a:1016237426846. Invest New Drugs. 2002. PMID: 12201492 Clinical Trial.

9

A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer.

Adjei AA, Dy GK, Erlichman C, Reid JM, Sloan JA, Pitot HC, Alberts SR, Goldberg RM, Hanson LJ, Atherton PJ, Watanabe T, Geary RS, Holmlund J, Dorr FA. Adjei AA, et al. Clin Cancer Res. 2003 Jan;9(1):115-23. Clin Cancer Res. 2003. PMID: 12538459 Clinical Trial.

10

Phase II study of the farnesyl transferase inhibitor R115777 in patients with advanced non-small-cell lung cancer.

Adjei AA, Mauer A, Bruzek L, Marks RS, Hillman S, Geyer S, Hanson LJ, Wright JJ, Erlichman C, Kaufmann SH, Vokes EE. Adjei AA, et al. J Clin Oncol. 2003 May 1;21(9):1760-6. doi: 10.1200/JCO.2003.09.075. J Clin Oncol. 2003. PMID: 12721252 Clinical Trial.

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