Akey DL - Search Results

1

A 7μm mini-beam improves diffraction data from small or imperfect crystals of macromolecules.

Sanishvili R, Nagarajan V, Yoder D, Becker M, Xu S, Corcoran S, Akey DL, Smith JL, Fischetti RF. Sanishvili R, et al. Among authors: akey dl. Acta Crystallogr D Biol Crystallogr. 2008 Apr;64(Pt 4):425-35. doi: 10.1107/S0907444908001741. Epub 2008 Mar 19. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 18391409 Free PMC article.

2

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

3

Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.

Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA. Giraldes JW, et al. Among authors: akey dl. Nat Chem Biol. 2006 Oct;2(10):531-6. doi: 10.1038/nchembio822. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969373

4

Structure and functional analysis of RifR, the type II thioesterase from the rifamycin biosynthetic pathway.

Claxton HB, Akey DL, Silver MK, Admiraal SJ, Smith JL. Claxton HB, et al. Among authors: akey dl. J Biol Chem. 2009 Feb 20;284(8):5021-9. doi: 10.1074/jbc.M808604200. Epub 2008 Dec 22. J Biol Chem. 2009. PMID: 19103602 Free PMC article.

5

Use of massively multiple merged data for low-resolution S-SAD phasing and refinement of flavivirus NS1.

Akey DL, Brown WC, Konwerski JR, Ogata CM, Smith JL. Akey DL, et al. Acta Crystallogr D Biol Crystallogr. 2014 Oct;70(Pt 10):2719-29. doi: 10.1107/S1399004714017556. Epub 2014 Sep 27. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25286855 Free PMC article.

6

Efficient merging of data from multiple samples for determination of anomalous substructure.

Akey DL, Terwilliger TC, Smith JL. Akey DL, et al. Acta Crystallogr D Struct Biol. 2016 Mar;72(Pt 3):296-302. doi: 10.1107/S2059798315021920. Epub 2016 Mar 1. Acta Crystallogr D Struct Biol. 2016. PMID: 26960117 Free PMC article.

7

Can I solve my structure by SAD phasing? Anomalous signal in SAD phasing.

Terwilliger TC, Bunkóczi G, Hung LW, Zwart PH, Smith JL, Akey DL, Adams PD. Terwilliger TC, et al. Among authors: akey dl. Acta Crystallogr D Struct Biol. 2016 Mar;72(Pt 3):346-58. doi: 10.1107/S2059798315019269. Epub 2016 Mar 1. Acta Crystallogr D Struct Biol. 2016. PMID: 26960122 Free PMC article.

8

Can I solve my structure by SAD phasing? Planning an experiment, scaling data and evaluating the useful anomalous correlation and anomalous signal.

Terwilliger TC, Bunkóczi G, Hung LW, Zwart PH, Smith JL, Akey DL, Adams PD. Terwilliger TC, et al. Among authors: akey dl. Acta Crystallogr D Struct Biol. 2016 Mar;72(Pt 3):359-74. doi: 10.1107/S2059798315019403. Epub 2016 Mar 1. Acta Crystallogr D Struct Biol. 2016. PMID: 26960123 Free PMC article.

9

Thiosulfate sulfurtransferase-like domain-containing 1 protein interacts with thioredoxin.

Libiad M, Motl N, Akey DL, Sakamoto N, Fearon ER, Smith JL, Banerjee R. Libiad M, et al. Among authors: akey dl. J Biol Chem. 2018 Feb 23;293(8):2675-2686. doi: 10.1074/jbc.RA117.000826. Epub 2018 Jan 18. J Biol Chem. 2018. PMID: 29348167 Free PMC article.

10

Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.

Akey DL, Razelun JR, Tehranisa J, Sherman DH, Gerwick WH, Smith JL. Akey DL, et al. Structure. 2010 Jan 13;18(1):94-105. doi: 10.1016/j.str.2009.10.018. Structure. 2010. PMID: 20152156 Free PMC article.

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