Austin CP - Search Results

1

A bioluminescent cytotoxicity assay for assessment of membrane integrity using a proteolytic biomarker.

Cho MH, Niles A, Huang R, Inglese J, Austin CP, Riss T, Xia M. Cho MH, et al. Among authors: austin cp. Toxicol In Vitro. 2008 Jun;22(4):1099-106. doi: 10.1016/j.tiv.2008.02.013. Epub 2008 Mar 4. Toxicol In Vitro. 2008. PMID: 18400464 Free PMC article.

2

Characterization of diversity in toxicity mechanism using in vitro cytotoxicity assays in quantitative high throughput screening.

Huang R, Southall N, Cho MH, Xia M, Inglese J, Austin CP. Huang R, et al. Among authors: austin cp. Chem Res Toxicol. 2008 Mar;21(3):659-67. doi: 10.1021/tx700365e. Epub 2008 Feb 19. Chem Res Toxicol. 2008. PMID: 18281954 Free PMC article.

3

Compound cytotoxicity profiling using quantitative high-throughput screening.

Xia M, Huang R, Witt KL, Southall N, Fostel J, Cho MH, Jadhav A, Smith CS, Inglese J, Portier CJ, Tice RR, Austin CP. Xia M, et al. Among authors: austin cp. Environ Health Perspect. 2008 Mar;116(3):284-91. doi: 10.1289/ehp.10727. Environ Health Perspect. 2008. PMID: 18335092 Free PMC article.

4

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Among authors: austin cp. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

5

A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression.

Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. Johnson RL, et al. Among authors: austin cp. Anal Biochem. 2008 Apr 15;375(2):237-48. doi: 10.1016/j.ab.2007.12.028. Epub 2007 Dec 25. Anal Biochem. 2008. PMID: 18211814 Free PMC article.

6

Identification of a potent new chemotype for the selective inhibition of PDE4.

Skoumbourdis AP, Huang R, Southall N, Leister W, Guo V, Cho MH, Inglese J, Nirenberg M, Austin CP, Xia M, Thomas CJ. Skoumbourdis AP, et al. Among authors: austin cp. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1297-303. doi: 10.1016/j.bmcl.2008.01.028. Epub 2008 Jan 11. Bioorg Med Chem Lett. 2008. PMID: 18243697 Free PMC article.

7

Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory.

Xia M, Huang R, Guo V, Southall N, Cho MH, Inglese J, Austin CP, Nirenberg M. Xia M, et al. Among authors: austin cp. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2412-7. doi: 10.1073/pnas.0813020106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196967 Free PMC article.

8

Identification of chemical compounds that induce HIF-1alpha activity.

Xia M, Huang R, Sun Y, Semenza GL, Aldred SF, Witt KL, Inglese J, Tice RR, Austin CP. Xia M, et al. Among authors: austin cp. Toxicol Sci. 2009 Nov;112(1):153-63. doi: 10.1093/toxsci/kfp123. Epub 2009 Jun 5. Toxicol Sci. 2009. PMID: 19502547 Free PMC article.

9

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries.

Johnson RL, Huang R, Jadhav A, Southall N, Wichterman J, MacArthur R, Xia M, Bi K, Printen J, Austin CP, Inglese J. Johnson RL, et al. Among authors: austin cp. Mol Biosyst. 2009 Sep;5(9):1039-50. doi: 10.1039/b902021g. Epub 2009 Jun 19. Mol Biosyst. 2009. PMID: 19668870 Free PMC article.

10

Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features.

Huang R, Southall N, Xia M, Cho MH, Jadhav A, Nguyen DT, Inglese J, Tice RR, Austin CP. Huang R, et al. Among authors: austin cp. Toxicol Sci. 2009 Dec;112(2):385-93. doi: 10.1093/toxsci/kfp231. Epub 2009 Oct 4. Toxicol Sci. 2009. PMID: 19805409 Free PMC article.

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