De Jong D - Search Results

1

Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region.

Kozísek M, Sasková KG, Rezácová P, Brynda J, van Maarseveen NM, De Jong D, Boucher CA, Kagan RM, Nijhuis M, Konvalinka J. Kozísek M, et al. Among authors: de jong d. J Virol. 2008 Jun;82(12):5869-78. doi: 10.1128/JVI.02325-07. Epub 2008 Apr 9. J Virol. 2008. PMID: 18400858 Free PMC article.

2

Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC).

Schuurman R, Nijhuis M, van Leeuwen R, Schipper P, de Jong D, Collis P, Danner SA, Mulder J, Loveday C, Christopherson C, et al. Schuurman R, et al. Among authors: de jong d. J Infect Dis. 1995 Jun;171(6):1411-9. doi: 10.1093/infdis/171.6.1411. J Infect Dis. 1995. PMID: 7539472

3

Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assay.

Boucher CA, Keulen W, van Bommel T, Nijhuis M, de Jong D, de Jong MD, Schipper P, Back NK. Boucher CA, et al. Among authors: de jong d, de jong md. Antimicrob Agents Chemother. 1996 Oct;40(10):2404-9. doi: 10.1128/AAC.40.10.2404. Antimicrob Agents Chemother. 1996. PMID: 8891152 Free PMC article.

4

Lamivudine-resistant human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-resistant to zidovudine in vivo.

Nijhuis M, Schuurman R, de Jong D, van Leeuwen R, Lange J, Danner S, Keulen W, de Groot T, Boucher CA. Nijhuis M, et al. Among authors: de jong d, de groot t. J Infect Dis. 1997 Aug;176(2):398-405. doi: 10.1086/514056. J Infect Dis. 1997. PMID: 9237704

5

Efficacy of adding indinavir to previous reverse transcriptase nucleoside analogues in relation to genotypic and phenotypic resistance development in advanced HIV-1-infected patients.

Ruiz L, Nijhuis M, Boucher C, Puig T, Bonjoch A, Martínez-Picado J, Marfil S, de Jong D, Burger D, Arnó A, Balagué M, Clotet B. Ruiz L, et al. Among authors: de jong d. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Sep 1;19(1):19-28. doi: 10.1097/00042560-199809010-00003. J Acquir Immune Defic Syndr Hum Retrovirol. 1998. PMID: 9732064 Clinical Trial.

6

Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy.

Nijhuis M, Schuurman R, de Jong D, Erickson J, Gustchina E, Albert J, Schipper P, Gulnik S, Boucher CA. Nijhuis M, et al. Among authors: de jong d. AIDS. 1999 Dec 3;13(17):2349-59. doi: 10.1097/00002030-199912030-00006. AIDS. 1999. PMID: 10597776

7

Transient relapses ("blips") of plasma HIV RNA levels during HAART are associated with drug resistance.

Cohen Stuart JW, Wensing AM, Kovacs C, Righart M, de Jong D, Kaye S, Schuurman R, Visser CJ, Boucher CA. Cohen Stuart JW, et al. Among authors: de jong d. J Acquir Immune Defic Syndr. 2001 Oct 1;28(2):105-13. doi: 10.1097/00042560-200110010-00001. J Acquir Immune Defic Syndr. 2001. PMID: 11588503

8

A novel real-time PCR assay to determine relative replication capacity for HIV-1 protease variants and/or reverse transcriptase variants.

van Maarseveen NM, Huigen MC, de Jong D, Smits AM, Boucher CA, Nijhuis M. van Maarseveen NM, et al. Among authors: de jong d. J Virol Methods. 2006 May;133(2):185-94. doi: 10.1016/j.jviromet.2005.11.008. Epub 2005 Dec 20. J Virol Methods. 2006. PMID: 16368153

9

An increase in viral replicative capacity drives the evolution of protease inhibitor-resistant human immunodeficiency virus type 1 in the absence of drugs.

van Maarseveen NM, de Jong D, Boucher CA, Nijhuis M. van Maarseveen NM, et al. Among authors: de jong d. J Acquir Immune Defic Syndr. 2006 Jun;42(2):162-8. doi: 10.1097/01.qai.0000219787.65915.56. J Acquir Immune Defic Syndr. 2006. PMID: 16645546

10

Persistence of HIV-1 variants with multiple protease inhibitor (PI)-resistance mutations in the absence of PI therapy can be explained by compensatory fixation.

van Maarseveen NM, Wensing AM, de Jong D, Taconis M, Borleffs JC, Boucher CA, Nijhuis M. van Maarseveen NM, et al. Among authors: de jong d. J Infect Dis. 2007 Feb 1;195(3):399-409. doi: 10.1086/510533. Epub 2006 Dec 29. J Infect Dis. 2007. PMID: 17205479

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