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mTORC1 promotes survival through translational control of Mcl-1.
Mills JR, Hippo Y, Robert F, Chen SM, Malina A, Lin CJ, Trojahn U, Wendel HG, Charest A, Bronson RT, Kogan SC, Nadon R, Housman DE, Lowe SW, Pelletier J. Mills JR, et al. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10853-8. doi: 10.1073/pnas.0804821105. Epub 2008 Jul 29. Proc Natl Acad Sci U S A. 2008. PMID: 18664580 Free PMC article.
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. Wendel HG, et al. Among authors: kogan s. Nature. 2004 Mar 18;428(6980):332-7. doi: 10.1038/nature02369. Nature. 2004. PMID: 15029198 Free article.
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition.
Wendel HG, de Stanchina E, Cepero E, Ray S, Emig M, Fridman JS, Veach DR, Bornmann WG, Clarkson B, McCombie WR, Kogan SC, Hochhaus A, Lowe SW. Wendel HG, et al. Among authors: kogan sc. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7444-9. doi: 10.1073/pnas.0602402103. Epub 2006 May 1. Proc Natl Acad Sci U S A. 2006. PMID: 16651519 Free PMC article.
Mouse models of human AML accurately predict chemotherapy response.
Zuber J, Radtke I, Pardee TS, Zhao Z, Rappaport AR, Luo W, McCurrach ME, Yang MM, Dolan ME, Kogan SC, Downing JR, Lowe SW. Zuber J, et al. Among authors: kogan sc. Genes Dev. 2009 Apr 1;23(7):877-89. doi: 10.1101/gad.1771409. Genes Dev. 2009. PMID: 19339691 Free PMC article.
Direct and indirect targeting of MYC to treat acute myeloid leukemia.
Brondfield S, Umesh S, Corella A, Zuber J, Rappaport AR, Gaillard C, Lowe SW, Goga A, Kogan SC. Brondfield S, et al. Among authors: kogan sc. Cancer Chemother Pharmacol. 2015 Jul;76(1):35-46. doi: 10.1007/s00280-015-2766-z. Epub 2015 May 9. Cancer Chemother Pharmacol. 2015. PMID: 25956709 Free PMC article.
489 results