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Page 1
Antitopes define preferential proteasomal cleavage site usage.
Strehl B, Textoris-Taube K, Jäkel S, Voigt A, Henklein P, Steinhoff U, Kloetzel PM, Kuckelkorn U. Strehl B, et al. Among authors: jakel s. J Biol Chem. 2008 Jun 27;283(26):17891-7. doi: 10.1074/jbc.M710042200. Epub 2008 Apr 18. J Biol Chem. 2008. PMID: 18424434 Free article.
Amyloid-associated hyperconnectivity drives tau spread across connected brain regions in Alzheimer's disease.
Roemer-Cassiano SN, Wagner F, Evangelista L, Rauchmann BS, Dehsarvi A, Steward A, Dewenter A, Biel D, Zhu Z, Pescoller J, Gross M, Perneczky R, Malpetti M, Ewers M, Schöll M, Dichgans M, Höglinger GU, Brendel M, Jäkel S, Franzmeier N. Roemer-Cassiano SN, et al. Among authors: jakel s. Sci Transl Med. 2025 Jan 22;17(782):eadp2564. doi: 10.1126/scitranslmed.adp2564. Epub 2025 Jan 22. Sci Transl Med. 2025. PMID: 39841807
snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses.
Macnair W, Calini D, Agirre E, Bryois J, Jäkel S, Smith RS, Kukanja P, Stokar-Regenscheit N, Ott V, Foo LC, Collin L, Schippling S, Urich E, Nutma E, Marzin M, Ansaloni F, Amor S, Magliozzi R, Heidari E, Robinson MD, Ffrench-Constant C, Castelo-Branco G, Williams A, Malhotra D. Macnair W, et al. Among authors: jakel s. Neuron. 2024 Dec 20:S0896-6273(24)00873-0. doi: 10.1016/j.neuron.2024.11.016. Online ahead of print. Neuron. 2024. PMID: 39708806 Free article.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: jakel s. Immunity. 2025 Jan 14;58(1):263. doi: 10.1016/j.immuni.2024.11.024. Epub 2024 Dec 4. Immunity. 2025. PMID: 39637851 No abstract available.
Mapping the glial transcriptome in Huntington's disease using snRNAseq: selective disruption of glial signatures across brain regions.
Bøstrand SMK, Seeker LA, Bestard-Cuche N, Kazakou NL, Jäkel S, Kenkhuis B, Henderson NC, de Bot ST, van Roon-Mom WMC, Priller J, Williams A. Bøstrand SMK, et al. Among authors: jakel s. Acta Neuropathol Commun. 2024 Oct 21;12(1):165. doi: 10.1186/s40478-024-01871-3. Acta Neuropathol Commun. 2024. PMID: 39428482 Free PMC article.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Among authors: jakel s. Immunity. 2024 Nov 12;57(11):2651-2668.e12. doi: 10.1016/j.immuni.2024.09.014. Epub 2024 Oct 16. Immunity. 2024. PMID: 39419029 Free article.
27 results