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In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria.
Wijnhoven TJ, Lensen JF, Wismans RG, Lamrani M, Monnens LA, Wevers RA, Rops AL, van der Vlag J, Berden JH, van den Heuvel LP, van Kuppevelt TH. Wijnhoven TJ, et al. Among authors: van kuppevelt th, van der vlag j, van den heuvel lp. J Am Soc Nephrol. 2007 Mar;18(3):823-32. doi: 10.1681/ASN.2006070692. Epub 2007 Jan 24. J Am Soc Nephrol. 2007. Retraction in: J Am Soc Nephrol. 2008 Mar;19(3):647. PMID: 17251387 Free article. Retracted.
Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly.
Vogel RO, Janssen RJ, van den Brand MA, Dieteren CE, Verkaart S, Koopman WJ, Willems PH, Pluk W, van den Heuvel LP, Smeitink JA, Nijtmans LG. Vogel RO, et al. Among authors: van den brand ma, van den heuvel lp. Genes Dev. 2007 Mar 1;21(5):615-24. doi: 10.1101/gad.408407. Genes Dev. 2007. PMID: 17344420 Free PMC article.
Adult and paediatric patients with minimal change nephrotic syndrome show no major alterations in glomerular expression of sulphated heparan sulphate domains.
Wijnhoven TJ, Geelen JM, Bakker M, Lensen JF, Rops AL, Kramer AB, Navis G, van den Hoven MJ, van der Vlag J, Berden JH, Wetzels JF, van den Heuvel LP, Monnens LA, van Kuppevelt TH. Wijnhoven TJ, et al. Among authors: van den hoven mj, van kuppevelt th, van der vlag j, van den heuvel lp. Nephrol Dial Transplant. 2007 Oct;22(10):2886-93. doi: 10.1093/ndt/gfm301. Epub 2007 May 25. Nephrol Dial Transplant. 2007. PMID: 17526541
Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens.
Willems E, Gloerich J, Suppers A, van der Flier M, van den Heuvel LP, van de Kar N, Philipsen RHLA, van Dael M, Kaforou M, Wright VJ, Herberg JA, Torres FM, Levin M, de Groot R, van Gool AJ, Lefeber DJ, Wessels HJCT, de Jonge MI; PERFORM consortium. Willems E, et al. Among authors: van gool aj, van dael m, van de kar n, van der flier m, van den heuvel lp. iScience. 2023 Jul 4;26(8):107257. doi: 10.1016/j.isci.2023.107257. eCollection 2023 Aug 18. iScience. 2023. PMID: 37520696 Free PMC article.
393 results