Iley J - Search Results

1

Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design.

Rodrigues T, Moreira R, Guedes RC, Iley J, Lopes F. Rodrigues T, et al. Among authors: iley j. Arch Pharm (Weinheim). 2008 Jun;341(6):344-50. doi: 10.1002/ardp.200700250. Arch Pharm (Weinheim). 2008. PMID: 18442019

2

Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: suppressing the rearrangement pathway in aqueous media.

Ribeiro L, Silva N, Iley J, Rautio J, Järvinen T, Mota-Filipe H, Moreira R, Mendes E. Ribeiro L, et al. Among authors: iley j. Arch Pharm (Weinheim). 2007 Jan;340(1):32-40. doi: 10.1002/ardp.200600145. Arch Pharm (Weinheim). 2007. PMID: 17206608

3

Acyloxymethyl as a drug protecting group. Part 6: N-acyloxymethyl- and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group.

Lopes F, Moreira R, Iley J. Lopes F, et al. Among authors: iley j. Bioorg Med Chem. 2000 Apr;8(4):707-16. doi: 10.1016/s0968-0896(00)00015-8. Bioorg Med Chem. 2000. PMID: 10819159

4

Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl esters as prodrugs of carboxylic acid agents.

Mendes E, Furtado T, Neres J, Iley J, Jarvinen T, Rautio J, Moreira R. Mendes E, et al. Among authors: iley j. Bioorg Med Chem. 2002 Mar;10(3):809-16. doi: 10.1016/s0968-0896(01)00336-4. Bioorg Med Chem. 2002. PMID: 11814870

5

Kinetics and mechanism of hydrolysis of N-acyloxymethyl derivatives of azetidin-2-one.

Valente E, Gomes JR, Moreira R, Iley J. Valente E, et al. Among authors: iley j. J Org Chem. 2004 May 14;69(10):3359-67. doi: 10.1021/jo0358123. J Org Chem. 2004. PMID: 15132543

6

Dipeptide vinyl sultams: synthesis via the Wittig-Horner reaction and activity against papain, falcipain-2 and Plasmodium falciparum.

Valente C, Guedes RC, Moreira R, Iley J, Gut J, Rosenthal PJ. Valente C, et al. Among authors: iley j. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4115-9. doi: 10.1016/j.bmcl.2006.04.079. Epub 2006 May 12. Bioorg Med Chem Lett. 2006. PMID: 16697641

7

Azetidine-2,4-diones (4-oxo-beta-lactams) as scaffolds for designing elastase inhibitors.

Mulchande J, Guedes RC, Tsang WY, Page MI, Moreira R, Iley J. Mulchande J, et al. Among authors: iley j. J Med Chem. 2008 Mar 27;51(6):1783-90. doi: 10.1021/jm701257h. Epub 2008 Feb 22. J Med Chem. 2008. PMID: 18290604

8

Dopamine- and tyramine-based derivatives of triazenes: activation by tyrosinase and implications for prodrug design.

Perry MJ, Mendes E, Simplício AL, Coelho A, Soares RV, Iley J, Moreira R, Francisco AP. Perry MJ, et al. Among authors: iley j. Eur J Med Chem. 2009 Aug;44(8):3228-34. doi: 10.1016/j.ejmech.2009.03.025. Epub 2009 Mar 27. Eur J Med Chem. 2009. PMID: 19386398 Free article.

9

A carbamate-based approach to primaquine prodrugs: antimalarial activity, chemical stability and enzymatic activation.

Mata G, do Rosário VE, Iley J, Constantino L, Moreira R. Mata G, et al. Among authors: iley j. Bioorg Med Chem. 2012 Jan 15;20(2):886-92. doi: 10.1016/j.bmc.2011.11.059. Epub 2011 Dec 3. Bioorg Med Chem. 2012. PMID: 22189276

10

Acyloxymethyl as a drug protecting group. Part 3. Tertiary O-amidomethyl esters of penicillin G: chemical hydrolysis and anti-bacterial activity.

Moreira R, Calheiros T, Cabrita J, Mendes E, Pimentel M, Iley J. Moreira R, et al. Among authors: iley j. Pharm Res. 1996 Jan;13(1):70-5. doi: 10.1023/a:1016077200460. Pharm Res. 1996. PMID: 8668682

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

46 results

Search Page

Filters