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LungVis 1.0: an automatic AI-powered 3D imaging ecosystem unveils spatial profiling of nanoparticle delivery and acinar migration of lung macrophages.
Yang L, Liu Q, Kumar P, Sengupta A, Farnoud A, Shen R, Trofimova D, Ziegler S, Davoudi N, Doryab A, Yildirim AÖ, Diefenbacher ME, Schiller HB, Razansky D, Piraud M, Burgstaller G, Kreyling WG, Isensee F, Rehberg M, Stoeger T, Schmid O. Yang L, et al. Among authors: diefenbacher me. Nat Commun. 2024 Nov 27;15(1):10138. doi: 10.1038/s41467-024-54267-1. Nat Commun. 2024. PMID: 39604430 Free PMC article.
An oral non-covalent non-peptidic inhibitor of SARS-CoV-2 Mpro ameliorates viral replication and pathogenesis in vivo.
Zhou NE, Tang S, Bian X, Parai MK, Krieger IV, Flores A, Jaiswal PK, Bam R, Wood JL, Shi Z, Stevens LJ, Scobey T, Diefenbacher MV, Moreira FR, Baric TJ, Acharya A, Shin J, Rathi MM, Wolff KC, Riva L, Bakowski MA, McNamara CW, Catanzaro NJ, Graham RL, Schultz DC, Cherry S, Kawaoka Y, Halfmann PJ, Baric RS, Denison MR, Sheahan TP, Sacchettini JC. Zhou NE, et al. Among authors: diefenbacher mv. Cell Rep. 2024 Nov 26;43(11):114929. doi: 10.1016/j.celrep.2024.114929. Epub 2024 Nov 5. Cell Rep. 2024. PMID: 39504242 Free article.
USP10 drives cancer stemness and enables super-competitor signalling in colorectal cancer.
Reissland M, Hartmann O, Tauch S, Bugter JM, Prieto-Garcia C, Schulte C, Loebbert S, Solvie D, Bitman-Lotan E, Narain A, Jacomin AC, Schuelein-Voelk C, Fuss CT, Pahor N, Ade C, Buck V, Potente M, Li V, Beliu G, Wiegering A, Grossmann T, Eilers M, Wolf E, Maric H, Rosenfeldt M, Maurice MM, Dikic I, Gallant P, Orian A, Diefenbacher ME. Reissland M, et al. Among authors: diefenbacher me. Oncogene. 2024 Dec;43(50):3645-3659. doi: 10.1038/s41388-024-03141-x. Epub 2024 Oct 23. Oncogene. 2024. PMID: 39443725 Free PMC article.
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/2.
Vogt M, Dudvarski Stankovic N, Cruz Garcia Y, Hofstetter J, Schneider K, Kuybu F, Hauck T, Adhikari B, Hamann A, Rocca Y, Grysczyk L, Martin B, Gebhardt-Wolf A, Wiegering A, Diefenbacher M, Gasteiger G, Knapp S, Saur D, Eilers M, Rosenfeldt M, Erhard F, Vos SM, Wolf E. Vogt M, et al. Among authors: diefenbacher m. Gut. 2024 Aug 8;73(9):1509-1528. doi: 10.1136/gutjnl-2023-331519. Gut. 2024. PMID: 38821858 Free PMC article.
The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronaviruses.
Martinez DR, Moreira FR, Catanzaro NJ, Diefenbacher MV, Zweigart MR, Gully KL, De la Cruz G, Brown AJ, Adams LE, Yount B, Baric TJ, Mallory ML, Conrad H, May SR, Dong S, Scobey DT, Nguyen C, Montgomery SA, Perry JK, Babusis D, Barrett KT, Nguyen AH, Nguyen AQ, Kalla R, Bannister R, Feng JY, Cihlar T, Baric RS, Mackman RL, Bilello JP, Schäfer A, Sheahan TP. Martinez DR, et al. Among authors: diefenbacher mv. Sci Transl Med. 2024 May 22;16(748):eadj4504. doi: 10.1126/scitranslmed.adj4504. Epub 2024 May 22. Sci Transl Med. 2024. PMID: 38776389 Free PMC article.
Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.
Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, Orton R, Sloan E, Güereca M, Feltman EM, Smollett K, da Silva Filipe A, Conley M, Russell AB, Brooke CB, Hutchinson E, Mehle A. Ranum JN, et al. Among authors: diefenbacher m. Nucleic Acids Res. 2024 Apr 12;52(6):3199-3212. doi: 10.1093/nar/gkae133. Nucleic Acids Res. 2024. PMID: 38407436 Free PMC article.
Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.
Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, Orton R, Sloan E, Guereca M, Feltman EM, Smollett K, da Silva Filipe A, Conley M, Russell AB, Brooke CB, Hutchinson E, Mehle A. Ranum JN, et al. Among authors: diefenbacher m. bioRxiv [Preprint]. 2024 Feb 7:2023.12.12.570638. doi: 10.1101/2023.12.12.570638. bioRxiv. 2024. Update in: Nucleic Acids Res. 2024 Apr 12;52(6):3199-3212. doi: 10.1093/nar/gkae133 PMID: 38168266 Free PMC article. Updated. Preprint.
61 results